Atopic dermatitis (AD) is an eczematous, pruritic skin disorder with extensive barrier
dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction …

The cytokine interleukin‐31 has been implicated in the pathophysiology of multiple atopic
disorders such as atopic dermatitis (AD), allergic rhinitis, and airway hyper‐reactivity. In AD …

T helper-17 (Th17) cells, which mainly produce IL-17, are associated with development of
various autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases …

Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intense
pruritus and recurrent eczematous lesions that significantly impair quality of life. It is a …

Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction, and chronic
pruritus. As the anti-interleukin-4 (IL-4) receptor α antibody dupilumab improves all three …

The aryl hydrocarbon receptor (AHR)/AHR-nuclear translocator (ARNT) system is a sensitive
sensor for small molecular, xenobiotic chemicals of exogenous and endogenous origin …

Background Pruritus (itch) is a cardinal symptom in atopic dermatitis (AD). Objective To
evaluate the timing and effect of dupilumab on itch. Methods Analysis of data from 1505 …

Type 2 immunity evolved to combat helminth infections by orchestrating a combined
protective response of innate and adaptive immune cells and promotion of parasitic worm …

Skin inflammation often evokes pruritus, which is the major subjective symptom in many
inflammatory skin diseases such as atopic dermatitis and prurigo nodularis. Pruritus or itch is …

Atopic dermatitis (AD) is an immune-mediated inflammatory skin disease characterized by a
predominant type 2 immune response. Type 2 immunity is driven by multiple cytokines …