The study of the immunoskeletal interface has led to the discovery of numerous cytokines
involved in the regulation of bone remodeling, providing valuable information on the …

Background Our knowledge of etiopathogenesis of atopic dermatitis (AD) is largely derived
from skin biopsies, which are associated with pain, scarring and infection. In contrast, tape …

Dupilumab is a monoclonal antibody approved for the treatment of moderate‐to‐severe
atopic dermatitis (AD) in patients aged≥ 12 years. Large, double‐blind, randomized …

Allergic diseases are important diseases that affect many patients worldwide. Over the past
few decades, the incidence of allergic diseases has increased significantly due to social …

Atopic dermatitis (AD) is a prototypic inflammatory disease that presents with intense itching.
The pathophysiology of AD is multifactorial, involving environmental factors, genetic …

Background Pruritus is the most common symptom in patients with skin disease. Psoriasis
and atopic dermatitis are clinically distinct inflammatory diseases. Interleukins are cytokines …

Aryl hydrocarbon receptor (AHR)/nuclear factor‐erythroid 2‐related factor 2 (NRF2)
modulation is emerging as novel targets in the treatment of atopic dermatitis and other …

Atopic dermatitis (AD) is a chronic inflammatory disease with a heterogeneous pathogenesis
correlated with dysregulation of the immune system and a prevalence of the T2-mediated …

Interleukin 31 belongs to the IL-6 superfamily, and it is an itch mediator already studied in
several diseases, comprising atopic dermatitis, allergic pathologies, and onco …

Mechanical scratching, a common external stress affecting the skin, is induced by various
causes, such as pruritus. Scratch injury to epidermal keratinocytes upregulates the …