Paracetamol: a review of guideline recommendations

U Freo, C Ruocco, A Valerio, I Scagnol… - Journal of clinical …, 2021 - mdpi.com
Musculoskeletal pain conditions are age-related, leading contributors to chronic pain and
pain-related disability, which are expected to rise with the rapid global population aging …

The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

GG Graham, MJ Davies, RO Day, A Mohamudally… - …, 2013 - Springer
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …

Comparative study of inhibition mechanisms of structurally different flavonoid compounds on α-glucosidase and synergistic effect with acarbose

J Yang, X Wang, C Zhang, L Ma, T Wei, Y Zhao… - Food chemistry, 2021 - Elsevier
Flavonoid compounds have anti-diabetic activity, which can control blood glucose levels by
inhibiting α-glucosidase activity. In this paper, the inhibition mechanisms between four …

Inhibitory mechanism of apigenin on α-glucosidase and synergy analysis of flavonoids

L Zeng, G Zhang, S Lin, D Gong - Journal of Agricultural and Food …, 2016 - ACS Publications
Inhibition of α-glucosidase activity may suppress postprandial hyperglycemia. The inhibition
kinetic analysis showed that apigenin reversibly inhibited α-glucosidase activity with an IC50 …

Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain

CKS Ong, RA Seymour, P Lirk… - Anesthesia & Analgesia, 2010 - journals.lww.com
BACKGROUND: There has been a trend over recent years for combining a nonsteroidal
antiinflammatory drug (NSAID) with paracetamol (acetaminophen) for pain management …

[图书][B] Pain Assessment and Pharmacologic Management-E-Book: Pain Assessment and Pharmacologic Management-E-Book

C Pasero, M McCaffery - 2010 - books.google.com
Pain Assessment and Pharmacologic Management, by highly renowned authors Chris
Pasero and Margo McCaffery, is destined to become the definitive resource in pain …

An updated review on the metabolite (AM404)-mediated central mechanism of action of paracetamol (acetaminophen): experimental evidence and potential clinical …

C Mallet, J Desmeules, R Pegahi… - Journal of Pain …, 2023 - Taylor & Francis
Paracetamol remains the recommended first-line option for mild-to-moderate acute pain in
general population and particularly in vulnerable populations. Despite its wide use, debate …

Nonsteroidal anti-inflammatory drugs for managing postoperative endodontic pain in patients who present with preoperative pain: a systematic review and meta …

EA Smith, JG Marshall, SS Selph, DR Barker… - Journal of …, 2017 - Elsevier
Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) have been commonly used to
treat endodontic postoperative pain. The purpose of this study was to address the following …

Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin

K Mishra, AP Dash, BK Swain, N Dey - Malaria journal, 2009 - Springer
Abstract Background Herbal extracts of Andrographis paniculata (AP) and Hedyotis
corymbosa (HC) are known as hepato-protective and fever-reducing drugs since ancient …

[HTML][HTML] Therapeutic efficacy of Clompanus pubescens leaves fractions via downregulation of neuronal cholinesterases/Na+-K+ ATPase/IL-1 β, and improving the …

AS Onikanni, B Lawal, BE Oyinloye… - Biomedicine & …, 2022 - Elsevier
The increasing global burden of diabetes mellitus has called for the search for a therapeutic
alternative that offers better activities and safety than conventional chemotherapy. Herein …