Next‐generation industrial biotechnology‐transforming the current industrial biotechnology into competitive processes

LP Yu, FQ Wu, GQ Chen - Biotechnology Journal, 2019 - Wiley Online Library
The chemical industry has made a contribution to modern society by providing cost‐
competitive products for our daily use. However, it now faces a serious challenge regarding …

How microbes tolerate ethanol and butanol

S Liu, N Qureshi - New biotechnology, 2009 - Elsevier
New robust biocatalysts are needed to depolymerize or hydrolyze recalcitrant
heterogeneous lignocellulosic biomass polymers into monomers and to convert the mixed …

Reconstructing the clostridial n-butanol metabolic pathway in Lactobacillus brevis

OV Berezina, NV Zakharova, A Brandt… - Applied microbiology …, 2010 - Springer
A Lactobacillus brevis strain with the ability to synthesize butanol from glucose was
constructed by metabolic engineering. The genes crt, bcd, etfB, etfA, and hbd, composing …

Biosynthesis of cis,cis-Muconic Acid and Its Aromatic Precursors, Catechol and Protocatechuic Acid, from Renewable Feedstocks by Saccharomyces cerevisiae

C Weber, C Brückner, S Weinreb, C Lehr… - Applied and …, 2012 - Am Soc Microbiol
Adipic acid is a high-value compound used primarily as a precursor for the synthesis of
nylon, coatings, and plastics. Today it is produced mainly in chemical processes from …

Advanced CRISPR/Cas-based genome editing tools for microbial biofuels production: a review

S Shanmugam, HH Ngo, YR Wu - Renewable Energy, 2020 - Elsevier
With rapid progress in the fields of synthetic biology and metabolic engineering, there are
possible applications to generate a wide range of advanced biofuels with maximized yield …

Construction of a controllable β‐carotene biosynthetic pathway by decentralized assembly strategy in Saccharomyces cerevisiae

W Xie, M Liu, X Lv, W Lu, J Gu… - Biotechnology and …, 2014 - Wiley Online Library
Saccharomyces cerevisiae is an important platform organism for the synthesis of a great
number of natural products. However, the assembly of controllable and genetically stable …

Microbial production of advanced transportation fuels in non-natural hosts

MR Connor, JC Liao - Current opinion in biotechnology, 2009 - Elsevier
The production of alternative transportation fuels from renewable sources has gained
increased attention due to energy and environmental concerns. Recently, progress has …

Expanding the chemical palate of cells by combining systems biology and metabolic engineering

KA Curran, HS Alper - Metabolic engineering, 2012 - Elsevier
The field of Metabolic Engineering has recently undergone a transformation that has led to a
rapid expansion of the chemical palate of cells. Now, it is conceivable to produce nearly any …

Mathematical optimization applications in metabolic networks

AR Zomorrodi, PF Suthers, S Ranganathan… - Metabolic …, 2012 - Elsevier
Genome-scale metabolic models are increasingly becoming available for a variety of
microorganisms. This has spurred the development of a wide array of computational tools …

Novel T7-like expression systems used for Halomonas

H Zhao, HM Zhang, X Chen, T Li, Q Wu, Q Ouyang… - Metabolic …, 2017 - Elsevier
To engineer non-model organisms, suitable genetic parts must be available. However,
biological parts are often host strain sensitive. It is therefore necessary to develop genetic …