Integrating liquid biopsies into the management of cancer

G Siravegna, S Marsoni, S Siena… - Nature reviews Clinical …, 2017 - nature.com
During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …

TGF‐β1/Smads and miR‐21 in Renal Fibrosis and Inflammation

A Loboda, M Sobczak, A Jozkowicz… - Mediators of …, 2016 - Wiley Online Library
Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic
kidney diseases. Increased apoptosis, epithelial‐to‐mesenchymal transition, and …

EVmiRNA: a database of miRNA profiling in extracellular vesicles

T Liu, Q Zhang, J Zhang, C Li, YR Miao… - Nucleic Acids …, 2019 - academic.oup.com
Extracellular vesicles (EVs), such as exosomes and microvesicles, acted as cell-to-cell
communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the …

The potential of microRNAs as prostate cancer biomarkers

L Fabris, Y Ceder, AM Chinnaiyan, GW Jenster… - European urology, 2016 - Elsevier
Abstract Context Short noncoding RNAs known as microRNAs (miRNAs) control protein
expression through the degradation of RNA or the inhibition of protein translation. The …

[HTML][HTML] The molecular profiling of solid tumors by liquid biopsy: A position paper of the AIOM–SIAPEC-IAP–SIBioC–SIC–SIF Italian Scientific Societies

A Russo, L Incorvaia, M Del Re, U Malapelle… - ESMO open, 2021 - Elsevier
The term liquid biopsy (LB) refers to the use of various biological fluids as a surrogate for
neoplastic tissue to achieve information for diagnostic, prognostic and predictive purposes …

Urine as a source of liquid biopsy for cancer

M Oshi, V Murthy, H Takahashi, M Huyser, M Okano… - Cancers, 2021 - mdpi.com
Simple Summary Tissue biopsy is essential for diagnosis and characterization of a tumor.
Recently circulating tumor cells and other tumor-derived nucleic acid can be detected from …

Human papillomaviruses-associated cancers: an update of current knowledge

E Pešut, A Đukić, L Lulić, J Skelin, I Šimić… - Viruses, 2021 - mdpi.com
Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses
infecting human epithelial cells, are associated with various benign and malignant lesions of …

Urine miRNA signature as a potential non-invasive diagnostic and prognostic biomarker in cervical cancer

M Aftab, SS Poojary, V Seshan, S Kumar, P Agarwal… - Scientific reports, 2021 - nature.com
MicroRNAs as cancer biomarkers in serum, plasma, and other body fluids are often used but
analysis of miRNA in urine is limited. We investigated the expression of selected miRNAs in …

MicroRNAs in chronic kidney disease: four candidates for clinical application

LJF Peters, J Floege, EAL Biessen… - International journal of …, 2020 - mdpi.com
There are still major challenges regarding the early diagnosis and treatment of chronic
kidney disease (CKD), which is in part due to the fact that its pathophysiology is very …

Prostate cancer detection and prognosis: from prostate specific antigen (PSA) to exosomal biomarkers

X Filella, L Foj - International journal of molecular sciences, 2016 - mdpi.com
Prostate specific antigen (PSA) remains the most used biomarker in the management of
early prostate cancer (PCa), in spite of the problems related to false positive results and …