Breast cancer care is complex and requires a multidisciplinary approach. In this study, we
provide an overview of current practices for the diagnosis and treatment of breast cancer for …

High-risk breast lesions, which comprise benign lesions and in situ carcinomas (lobular
carcinoma in situ and ductal carcinoma in situ), are clinically, morphologically, and …

Triple-negative breast cancer (TNBC) is an operational term that refers to a heterogeneous
collection of breast cancers lacking expression of estrogen receptor (ER), progesterone …

BACKGROUND: No consensus exists on the need to excise breast lesions that yield classic
lobular carcinoma in situ (LCIS) or atypical lobular hyperplasia (ALH)(known together as …

Background Lobular neoplasia (LN) includes atypical lobular hyperplasia (ALH) and lobular
carcinoma in situ (LCIS). LN often is an incidental finding on breast core needle biopsy …

Purpose Lobular carcinoma in situ (LCIS) is a marker of increased risk of breast cancer.
Current guidelines do not recommend mastectomy as a strategy for risk reduction for most …

Lobular carcinoma in situ (LCIS) is considered to be a risk factor for the development of
invasive breast carcinoma, but it may also be a non-obligate precursor to invasive lobular …

Comparing risk factor associations between invasive breast cancers and possible
precursors may further our understanding of factors related to initiation versus progression …

Background Recent evidence suggests that lobular carcinoma in situ (LCIS) can be a clonal
precursor of invasive breast cancers of both the ductal and lobular phenotypes. We sought …

Breast cancer (BC) prevention remains the ultimate cost-effective method to reduce the
global burden of invasive breast cancer (IBC). To date, surgery and chemoprevention …