Severe covid-19 pneumonia: pathogenesis and clinical management

AH Attaway, RG Scheraga, A Bhimraj, M Biehl… - bmj, 2021 - bmj.com
Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations

J Phua, L Weng, L Ling, M Egi, CM Lim… - The lancet respiratory …, 2020 - thelancet.com
Summary As coronavirus disease 2019 (COVID-19) spreads across the world, the intensive
care unit (ICU) community must prepare for the challenges associated with this pandemic …

ERS clinical practice guidelines: high-flow nasal cannula in acute respiratory failure

S Oczkowski, B Ergan, L Bos, M Chatwin… - European respiratory …, 2022 - Eur Respiratory Soc
Background High-flow nasal cannula (HFNC) has become a frequently used noninvasive
form of respiratory support in acute settings; however, evidence supporting its use has only …

The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline

B Rochwerg, S Einav, D Chaudhuri, J Mancebo… - Intensive care …, 2020 - Springer
Purpose High flow nasal cannula (HFNC) is a relatively recent respiratory support technique
which delivers high flow, heated and humidified controlled concentration of oxygen via the …

Effect of timing of intubation on clinical outcomes of critically ill patients with COVID-19: a systematic review and meta-analysis of non-randomized cohort studies

E Papoutsi, VG Giannakoulis, E Xourgia, C Routsi… - Critical Care, 2021 - Springer
Background Although several international guidelines recommend early over late intubation
of patients with severe coronavirus disease 2019 (COVID-19), this issue is still controversial …

The utility of high-flow nasal oxygen for severe COVID-19 pneumonia in a resource-constrained setting: A multi-centre prospective observational study

GL Calligaro, U Lalla, G Audley, P Gina, MG Miller… - …, 2020 - thelancet.com
Background The utility of heated and humidified high-flow nasal oxygen (HFNO) for severe
COVID-19-related hypoxaemic respiratory failure (HRF), particularly in settings with limited …

An index combining respiratory rate and oxygenation to predict outcome of nasal high-flow therapy

O Roca, B Caralt, J Messika, M Samper… - American journal of …, 2019 - atsjournals.org
Rationale: One important concern during high-flow nasal cannula (HFNC) therapy in
patients with acute hypoxemic respiratory failure is to not delay intubation. Objectives: To …

High-flow nasal cannula therapy in COVID-19: using the ROX index to predict success

A Chandel, S Patolia, AW Brown, AC Collins… - Respiratory …, 2021 - rc.rcjournal.com
BACKGROUND: Optimal timing of mechanical ventilation in COVID-19 is uncertain. We
sought to evaluate outcomes of delayed intubation and examine the ROX index (ie,[S pO 2/F …

High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure

R Mellado-Artigas, BL Ferreyro, F Angriman… - Critical Care, 2021 - Springer
Purpose Whether the use of high-flow nasal oxygen in adult patients with COVID-19
associated acute respiratory failure improves clinically relevant outcomes remains unclear …

Use of nasal high flow oxygen during acute respiratory failure

JD Ricard, O Roca, V Lemiale, A Corley… - Intensive care …, 2020 - Springer
Nasal high flow (NHF) has gained popularity among intensivists to manage patients with
acute respiratory failure. An important literature has accompanied this evolution. In this …