Potential therapeutic targets of quercetin, a plant flavonol, and its role in the therapy of various types of cancer through the modulation of various cell signaling …

SA Almatroodi, MA Alsahli, A Almatroudi, AK Verma… - Molecules, 2021 - mdpi.com
Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

A role for quercetin in coronavirus disease 2019 (COVID‐19)

G Derosa, P Maffioli, A D'Angelo… - Phytotherapy …, 2021 - Wiley Online Library
Several months ago, an outbreak of pneumonia of unknown aetiology was detected in
Wuhan City (China) and the aetiological agent of the atypical pneumonia was isolated by …

[HTML][HTML] Novel extraction, rapid assessment and bioavailability improvement of quercetin: A review

MF Manzoor, A Hussain, A Sameen, A Sahar… - Ultrasonics …, 2021 - Elsevier
Quercetin (QUR) have got the attention of scientific society frequently due to their wide range
of potential applications. QUR has been the focal point for research in various fields …

A review of the role of flavonoids in peptic ulcer (2010–2020)

C Serafim, ME Araruna, EA Júnior, M Diniz… - Molecules, 2020 - mdpi.com
Peptic ulcers are characterized by erosions on the mucosa of the gastrointestinal tract that
may reach the muscle layer. Their etiology is multifactorial and occurs when the balance …

Antioxidant role of kaempferol in prevention of hepatocellular carcinoma

N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …

Insight into polyphenol and gut microbiota crosstalk: are their metabolites the key to understand protective effects against metabolic disorders?

M Koudoufio, Y Desjardins, F Feldman, S Spahis… - Antioxidants, 2020 - mdpi.com
Lifestyle factors, especially diet and nutrition, are currently regarded as essential avenues to
decrease modern-day cardiometabolic disorders (CMD), including obesity, metabolic …

The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Kaempferol prevents acetaminophen-induced liver injury by suppressing hepatocyte ferroptosis via Nrf2 pathway activation

H Li, Q Weng, S Gong, W Zhang, J Wang, Y Huang… - Food & Function, 2023 - pubs.rsc.org
Acetaminophen (APAP)-induced liver injury (AILI) has become a growing public health
problem. Ferroptosis, an iron-dependent form of cell death associated with lipid peroxide …

Hydroxylation decoration patterns of flavonoids in horticultural crops: Chemistry, bioactivity, and biosynthesis

Y Liu, J Qian, J Li, M Xing, D Grierson… - Horticulture …, 2022 - academic.oup.com
Flavonoids are the most widespread polyphenolic compounds and are important dietary
constituents present in horticultural crops such as fruits, vegetables, and tea. Natural …

The efficacy of polyphenols as an antioxidant agent: An updated review

ME Abd El-Hack, MC de Oliveira, YA Attia… - International Journal of …, 2023 - Elsevier
Global production of the two major poultry products, meat and eggs, has increased quickly.
This, in turn, indicates both the relatively low cost and the customers' desire for these secure …