Neuroinflammation is a hallmark of many neurodegenerative diseases (NDs) and plays a
fundamental role in mediating the onset and progression of disease. Microglia, which …

Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …

Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …

Schizophrenia (SCZ) is a psychiatric disorder that can include symptoms of disorganized
speech and thoughts with uncertain underlying mechanisms possibly linked to over …

Schizophrenia is a psychiatric disorder with significant impact on individuals and society.
The current pharmacologic treatment, which principally alleviates psychosis, is focused on …

Schizophrenia and bipolar disorder are disabling psychiatric disorders with a worldwide
prevalence of approximately 1%. Both disorders present chronic and deteriorating …

Among the many brain abnormalities in schizophrenia are those related to mitochondrial
functions such as oxidative stress, energy metabolism and synaptic efficacy. The aim of this …

A diverse heterogeneity of microglial cells was previously described in Alzheimer's disease
(AD) pathology, including dark microglia, a state characterized by ultrastructural markers of …

Diffusion tensor imaging (DTI) is an imaging technique that uses magnetic resonance. It
measures the diffusion of water molecules in tissues, which can occur either without …