[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

The preconception environment and sperm epigenetics

C Marcho, OA Oluwayiose, JR Pilsner - Andrology, 2020 - Wiley Online Library
Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …

Epigenetic changes in sperm are associated with paternal and child quantitative autistic traits in an autism-enriched cohort

JI Feinberg, R Schrott, C Ladd-Acosta… - Molecular …, 2024 - nature.com
There is a need to consider paternal contributions to autism spectrum disorder (ASD) more
strongly. Autism etiology is complex, and heritability is not explained by genetics alone …

[HTML][HTML] Infertility in men: advances towards a comprehensive and integrative strategy for precision theranostics

M Assidi - Cells, 2022 - mdpi.com
Male infertility is an increasing and serious medical concern, though the mechanism
remains poorly understood. Impaired male reproductive function affects approximately half …

[HTML][HTML] Predicting male fertility from the sperm methylome: application to 120 bulls with hundreds of artificial insemination records

V Costes, A Chaulot-Talmon, E Sellem, JP Perrier… - Clinical …, 2022 - Springer
Background Conflicting results regarding alterations to sperm DNA methylation in cases of
spermatogenesis defects, male infertility and poor developmental outcomes have been …

High‐fat diets reduce male reproductive success in animal models: A systematic review and meta‐analysis

AJ Crean, AM Senior - Obesity Reviews, 2019 - Wiley Online Library
Sperm counts have shown a progressive decline across the world since the mid‐1900s.
Global rates of obesity have been climbing at a similarly alarming rate, suggesting that these …

[HTML][HTML] Mechanisms regulating mammalian spermatogenesis and fertility recovery following germ cell depletion

HM La, RM Hobbs - Cellular and Molecular Life Sciences, 2019 - Springer
Mammalian spermatogenesis is a highly complex multi-step process sustained by a
population of mitotic germ cells with self-renewal potential known as spermatogonial stem …

[HTML][HTML] Effect of paternal diet on spermatogenesis and offspring health: focus on epigenetics and interventions with food bioactive compounds

GFL Pascoal, MV Geraldi, MR Maróstica Jr, TP Ong - Nutrients, 2022 - mdpi.com
Infertility is a growing public health problem. Consumption of antioxidant bioactive food
compounds (BFCs) that include micronutrients and non-nutrients has been highlighted as a …

Potential implications of sperm DNA methylation functional properties in aquaculture management

S Zhang, Y Cheng, P Věchtová… - Reviews in …, 2023 - Wiley Online Library
The biology of fish sperm, an important topic in the research of reproduction and fisheries
from basic science to evolutionary and applied aspects, has implications for aquaculture …

[HTML][HTML] Biomaterials for Testicular Bioengineering: How far have we come and where do we have to go?

BO Horvath-Pereira, GHDR Almeida… - Frontiers in …, 2023 - frontiersin.org
Traditional therapeutic interventions aim to restore male fertile potential or preserve sperm
viability in severe cases, such as semen cryopreservation, testicular tissue, germ cell …