[HTML][HTML] Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer
Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …
heterogeneity of this disease presents a big challenge in its therapeutic management …
[HTML][HTML] Impact of the host response and osteoblast lineage cells on periodontal disease
M Zhou, DT Graves - Frontiers in immunology, 2022 - frontiersin.org
Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …
RNA-seq experiments have provided new insight into how resident cells and infiltrating …
[HTML][HTML] The role of natural products and their multitargeted approach to treat solid cancer
Natural products play a critical role in the discovery and development of numerous drugs for
the treatment of various types of cancer. These phytochemicals have demonstrated anti …
the treatment of various types of cancer. These phytochemicals have demonstrated anti …
[HTML][HTML] New directions in the therapy of glioblastoma
K Szklener, M Mazurek, M Wieteska, M Wacławska… - Cancers, 2022 - mdpi.com
Simple Summary Despite the continuous development of treatment technology,
glioblastoma remains a challenge for modern medicine. The standard of care remains a …
glioblastoma remains a challenge for modern medicine. The standard of care remains a …
[HTML][HTML] Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy
C Chang, W Guo, X Yu, C Guo, N Zhou, X Guo… - Materials Today Bio, 2023 - Elsevier
Bacteriophages (phages) are nanostructured viruses with highly selective antibacterial
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
[HTML][HTML] Role of plant-derived active constituents in cancer treatment and their mechanisms of action
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …
one of the main causes of death worldwide. Although substantial progress has been made …
FGFR families: biological functions and therapeutic interventions in tumors
Q Liu, J Huang, W Yan, Z Liu, S Liu, W Fang - MedComm, 2023 - Wiley Online Library
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …
[HTML][HTML] Medical biology of cancer-associated fibroblasts in pancreatic cancer
Simple Summary Pancreatic cancer is a very deadly form of cancer with a low survival rate.
One important characteristic of pancreatic cancer is the presence of a dense tissue called …
One important characteristic of pancreatic cancer is the presence of a dense tissue called …
[HTML][HTML] Angiogenesis in lung cancer: understanding the roles of growth factors
TYS Ngaha, AV Zhilenkova, FE Essogmo, IK Uchendu… - Cancers, 2023 - mdpi.com
Simple Summary Growth factors promote angiogenesis, which is a critical process in the
development of tumors. One of the therapeutic techniques being investigated in the …
development of tumors. One of the therapeutic techniques being investigated in the …