[HTML][HTML] Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer

F Ye, S Dewanjee, Y Li, NK Jha, ZS Chen, A Kumar… - Molecular cancer, 2023 - Springer
Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …

[HTML][HTML] Impact of the host response and osteoblast lineage cells on periodontal disease

M Zhou, DT Graves - Frontiers in immunology, 2022 - frontiersin.org
Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …

[HTML][HTML] The role of natural products and their multitargeted approach to treat solid cancer

N Muhammad, D Usmani, M Tarique, H Naz, M Ashraf… - Cells, 2022 - mdpi.com
Natural products play a critical role in the discovery and development of numerous drugs for
the treatment of various types of cancer. These phytochemicals have demonstrated anti …

[HTML][HTML] New directions in the therapy of glioblastoma

K Szklener, M Mazurek, M Wieteska, M Wacławska… - Cancers, 2022 - mdpi.com
Simple Summary Despite the continuous development of treatment technology,
glioblastoma remains a challenge for modern medicine. The standard of care remains a …

[HTML][HTML] Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy

C Chang, W Guo, X Yu, C Guo, N Zhou, X Guo… - Materials Today Bio, 2023 - Elsevier
Bacteriophages (phages) are nanostructured viruses with highly selective antibacterial
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …

New developments in the biology of fibroblast growth factors

DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

[HTML][HTML] Role of plant-derived active constituents in cancer treatment and their mechanisms of action

AW Khan, M Farooq, M Haseeb, S Choi - Cells, 2022 - mdpi.com
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …

FGFR families: biological functions and therapeutic interventions in tumors

Q Liu, J Huang, W Yan, Z Liu, S Liu, W Fang - MedComm, 2023 - Wiley Online Library
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …

[HTML][HTML] Medical biology of cancer-associated fibroblasts in pancreatic cancer

A Morgan, M Griffin, L Kameni, DC Wan, MT Longaker… - Biology, 2023 - mdpi.com
Simple Summary Pancreatic cancer is a very deadly form of cancer with a low survival rate.
One important characteristic of pancreatic cancer is the presence of a dense tissue called …

[HTML][HTML] Angiogenesis in lung cancer: understanding the roles of growth factors

TYS Ngaha, AV Zhilenkova, FE Essogmo, IK Uchendu… - Cancers, 2023 - mdpi.com
Simple Summary Growth factors promote angiogenesis, which is a critical process in the
development of tumors. One of the therapeutic techniques being investigated in the …