Microfluidics has emerged as a set of powerful tools that have greatly advanced some areas
of biological research, including research using C. elegans. The use of microfluidics has …

The development of therapeutic interventions for diseases necessitates a crucial step known
as drug screening, wherein potential substances with medicinal properties are rigorously …

Background Helminth parasites cause untold morbidity and mortality to billions of people
and livestock. Anthelmintic drugs are available but resistance is a problem in livestock …

The nematode (worm) Caenorhabditis elegans is one of the most widely studied organisms
for biomedical research. Currently, C. elegans assays are performed either on petri dishes …

Lab-on-a-chip (LoC) systems allow the implementation of benchtop analytical
methods/protocols using low reagent volumes, short processing times, and this potentially at …

Animal response to changes in environmental cues is a complex dynamical process that
occurs at diverse molecular and cellular levels. To gain a quantitative understanding of such …

Small multicellular organisms such as nematodes, fruit flies, clawed frogs, and zebrafish are
emerging models for an increasing number of biomedical and environmental studies. They …

This Account describes a strategy for fabricating multicomponent microsystems in which the
structures of essentially all of the components are formed in a single step of micromolding …

The nematode (worm) C. elegans is a leading multicellular animal model to study neuronal-
basis of behavior. Worms respond to a wide range of stimuli and exhibit characteristic …

The roundworm Caenorhabditis elegans (C. elegans) is a powerful model organism for
addressing fundamental biological questions related to human disease and aging. Its life …