RISUG® as a male contraceptive: journey from bench to bedside

B Khilwani, A Badar, AS Ansari, NK Lohiya - Basic and Clinical Andrology, 2020 - Springer
Even after decades of research men still lack reliable and reversible contraceptive methods
comparable to female methods of contraception. Traditional methods of male contraception …

RISUG: An intravasal injectable male contraceptive

NK Lohiya, I Alam, M Hussain, SR Khan… - Indian Journal of …, 2014 - journals.lww.com
Over the last two decades RISUG has been drawing attention in the field of male
contraception. It promises to sterile men for a period of up to 10-15 years. According to …

Safety & efficacy of an intravasal, one-time injectable & non-hormonal male contraceptive (RISUG): A clinical experience

RS Sharma, AK Mathur, R Singh, HC Das… - Indian Journal of …, 2019 - journals.lww.com
Methods: One hundred and thirty nine young males each having at least two children and
living with wife were given 120 μl of RISUG as bilateral vas intraluminal injection. After the …

Biophysical mechanism‐mediated time‐dependent effect on sperm of human and monkey vas implanted polyelectrolyte contraceptive

SK Guha - Asian journal of andrology, 2007 - Wiley Online Library
Aim: To determine the short and long‐term morphological effects on sperm as induced by
intra‐vas alteration of pH and electrical charge. Methods: Desired biophysical influences …

[PDF][PDF] Vas deferens, a site of male contraception: an overview

NK Lohiya, B Manivannan, PK Mishra… - Asian journal of …, 2001 - academia.edu
The vas deferens is a site which can be exploited for male contraception without undue side
effects. The only effective technique available for male contraception is vasectomy, being …

New technologies in contraception

S Rowlands - BJOG: An International Journal of Obstetrics & …, 2009 - Wiley Online Library
New technologies in both reversible contraception and sterilisation are described. The
review includes recent advances in the development of oral contraception, emergency …

RISUG™(reversible inhibition of sperm under guidance)–an antimicrobial as male vas deferens implant for HIV free semen

SK Guha - Medical hypotheses, 2005 - Elsevier
HIV transmission from the male to the female is a major health problem. A hypothesis
proposing an intra vas deferens implant of an antimicrobial compound to prevent the …

Evaluation of poly (styrene-alt-maleic anhydride)–ethanol as enteric coating material

X Lai, C Sun, H Tian, W Zhao, L Gao - International journal of …, 2008 - Elsevier
This study aims at evaluating the potential of SMA–ethanol as enteric coating polymer for
erythromycin tablets. SMA–ethanol was synthesized and characterized for physicochemical …

Effect of a new injectable male contraceptive on the seminal plasma amino acids studied by proton NMR spectroscopy

K Chaudhury, U Sharma, NR Jagannathan, SK Guha - Contraception, 2002 - Elsevier
Effect of RISUG™, a newly developed male contraceptive, on various amino acids of
seminal plasma ejaculates was studied by proton magnetic resonance spectroscopy at 400 …

Synthesis of fenoprofen and gemfibrozil styrene-maleic acid copolymer conjugates

M Zovko, M Barbarić, B Zorc, A Hafner… - Acta …, 2005 - repozitorij.unizg.hr
Two types of polymer-drug conjugates were synthesized starting from styrene-maleic acid
anhydride copolymer (SMA). Fenoprofen and gemfibrozil were chosen as model drugs …