Diagnosis and treatment of hepatocellular carcinoma. Update of the consensus document of the AEEH, AEC, SEOM, SERAM, SERVEI, and SETH

M Reig, A Forner, MA Ávila, C Ayuso, B Mínguez… - … Clínica (English Edition), 2021 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary liver neoplasm and one of the
most common causes of death in patients with cirrhosis of the liver. In parallel with …

Using circular RNA SMARCA5 as a potential novel biomarker for hepatocellular carcinoma

Z Li, YE Zhou, G Yang, S He, X Qiu, L Zhang, Q Deng… - Clinica chimica acta, 2019 - Elsevier
Background Hepatocellular carcinoma (HCC) is the most common malignant tumor
worldwide. Circular RNAs (circRNAs), a new class of endogenous non-coding RNAs, are …

CpG methylation signature predicts recurrence in early-stage hepatocellular carcinoma: results from a multicenter study

J Qiu, B Peng, Y Tang, Y Qian, P Guo, M Li… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Early-stage hepatocellular carcinoma (E-HCC) is being diagnosed increasingly,
and in one half of diagnosed patients, recurrence will develop. Thus, it is urgent to identify …

[HTML][HTML] LINC00152 promotes proliferation in hepatocellular carcinoma by targeting EpCAM via the mTOR signaling pathway

J Ji, J Tang, L Deng, Y Xie, R Jiang, G Li, B Sun - Oncotarget, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is well known as the sixth most common malignant tumor
and the third leading cause of cancer-related deaths globally. LINC00152 was documented …

Circulating tumor cells with stem-like phenotypes for diagnosis, prognosis, and therapeutic response evaluation in hepatocellular carcinoma

W Guo, YF Sun, MN Shen, XL Ma, J Wu, CY Zhang… - Clinical Cancer …, 2018 - AACR
Background: In the present study, we assessed the clinical value of circulating tumor cells
(CTC) with stem-like phenotypes for diagnosis, prognosis, and surveillance in hepatitis B …

Dickkopf-1: A promising target for cancer immunotherapy

HY Chu, Z Chen, L Wang, ZK Zhang, X Tan… - Frontiers in …, 2021 - frontiersin.org
Clinical studies in a range of cancers have detected elevated levels of the Wnt antagonist
Dickkopf-1 (DKK1) in the serum or tumors of patients, and this was frequently associated …

Multiplexed photoluminescent sensors: towards improved disease diagnostics

XP He, XL Hu, TD James, J Yoon, H Tian - Chemical Society Reviews, 2017 - pubs.rsc.org
The ability to simultaneously monitor multiple analytes in, for example, a single microplate
well, is important for both basic research and clinical applications. In particular, for disease …

[HTML][HTML] Serum biomarkers and ultrasensitive biosensors for diagnosis of early-stage hepatocellular carcinoma

LDS Lapitan Jr, M Pietrzak, M Krawczyk… - Sensors and Actuators B …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) was the third leading cause of cancer-related death
globally in 2020. The treatment of the disease is complex, with a high possibility of disease …

Rationale for targeting the Wnt signalling modulator Dickkopf‐1 for oncology

MH Kagey, X He - British journal of pharmacology, 2017 - Wiley Online Library
Wnt signalling is a fundamental pathway involved in embryonic development and adult
tissue homeostasis. Mutations in the pathway frequently lead to developmental defects and …

[HTML][HTML] Circulation long non-coding RNAs act as biomarkers for predicting tumorigenesis and metastasis in hepatocellular carcinoma

J Tang, R Jiang, L Deng, X Zhang, K Wang, B Sun - Oncotarget, 2015 - ncbi.nlm.nih.gov
METHODS In this study, we applied an lncRNA microarray to screen the potential biomarker
for HCC. The multi-stage validation and risk score formula detection was used for validation …