Sodium citrate 4% locking solution for central venous dialysis catheters—an effective, more cost-efficient alternative to heparin

L Grudzinski, P Quinan, S Kwok… - Nephrology Dialysis …, 2007 - academic.oup.com
Background. Thrombosis of the central venous haemodialysis catheter compromises
dialysis adequacy and catheter survival. Heparin containing catheter-locking solution has …

Antibiotic-based catheter lock solutions for prevention of catheter-related bloodstream infection: a systematic review of randomised controlled trials

M Snaterse, W Rüger, WJMS op Reimer… - Journal of Hospital …, 2010 - Elsevier
Catheter-related bloodstream infection (CRBSI) is associated with high rates of morbidity.
This systematic review assesses the efficacy of antibiotic-based lock solutions to prevent …

Prevention of hemodialysis catheter infections: Ointments, dressings, locks, and catheter hub devices

L Golestaneh, MH Mokrzycki - Hemodialysis International, 2018 - Wiley Online Library
Tunneled central venous catheters used for the provision of hemodialysis are associated
with excess morbidity and mortality. Catheter related exit site and blood stream infections …

A novel antimicrobial and antithrombotic lock solution for hemodialysis catheters: a multi-center, controlled, randomized trial

DG Maki, SR Ash, RK Winger, P Lavin… - Critical care …, 2011 - journals.lww.com
Background and Purpose: Catheter-related bloodstream infection is the greatest threat to the
safety of patients on hemodialysis. Catheter lock solutions containing heparin have been …

Full and Broad-Spectrum In Vivo Eradication of Catheter-Associated Biofilms Using Gentamicin-EDTA Antibiotic Lock Therapy

A Chauhan, D Lebeaux, JM Ghigo… - Antimicrobial agents and …, 2012 - Am Soc Microbiol
Biofilms that develop on indwelling devices are a major concern in clinical settings. While
removal of colonized devices remains the most frequent strategy for avoiding device-related …

The role of chelators in preventing biofilm formation and catheter-related bloodstream infections

II Raad, X Fang, XM Keutgen, Y Jiang… - Current opinion in …, 2008 - journals.lww.com
It is suggested that the addition of chelators such as ethylenediamine-tetraacetic acid and
citrate to antimicrobial lock solutions provides an innovative and superior alternative to …

A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis

LR Solomon, JS Cheesbrough, L Ebah… - American Journal of …, 2010 - Elsevier
BACKGROUND: Bacteremia is a major cause of morbidity in patients using intravascular
catheters. Interdialytic locking with antibiotics decreases the incidence of bacteremia, but …

[HTML][HTML] Infectious complications in dialysis—epidemiology and outcomes

PKT Li, KM Chow - Nature Reviews Nephrology, 2012 - nature.com
This Review focuses on the changing epidemiology of infections among patients with end-
stage renal disease who are undergoing dialysis. In particular, bloodstream infections …

[HTML][HTML] Taurolidine-based catheter lock regimen significantly reduces overall costs, infection, and dysfunction rates of tunneled hemodialysis catheters

W Winnicki, H Herkner, M Lorenz, A Handisurya… - Kidney international, 2018 - Elsevier
Catheter-related infections and dysfunction are the main catheter complications causing
morbidity and mortality in hemodialysis patients. However, there are no consistent data for …

Prevention of catheter-related bloodstream infection in patients on hemodialysis

MGH Betjes - Nature Reviews Nephrology, 2011 - nature.com
Central venous catheters (CVCs) are frequently used as vascular access for patients who
require hemodialysis, but infectious complications remain a major clinical problem …