[HTML][HTML] The role of glycolytic metabolic pathways in cardiovascular disease and potential therapeutic approaches
S Chen, Y Zou, C Song, K Cao, K Cai, Y Wu… - Basic Research in …, 2023 - Springer
Cardiovascular disease (CVD) is a major threat to human health, accounting for 46% of non-
communicable disease deaths. Glycolysis is a conserved and rigorous biological process …
communicable disease deaths. Glycolysis is a conserved and rigorous biological process …
A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy
GJ Yang, J Wu, CH Leung, DL Ma, J Chen - International Journal of …, 2021 - Elsevier
Glycolysis is an important step in respiration and provides energy for cellular processes.
Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, plays an important role …
Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, plays an important role …
[HTML][HTML] Effects of long-term cold stress on growth performance, behavior, physiological parameters, and energy metabolism in growing beef cattle
S Wang, Q Li, J Peng, H Niu - Animals, 2023 - mdpi.com
Simple Summary Winter cold stress is a major environmental factor affecting cattle industry
production in northern China. Determining the effects of prolonged cold stress on the …
production in northern China. Determining the effects of prolonged cold stress on the …
[HTML][HTML] Anti-Fatigue Effects of Lycium barbarum Polysaccharide and Effervescent Tablets by Regulating Oxidative Stress and Energy Metabolism in Rats
Y Peng, L Zhao, K Hu, Y Yang, J Ma, Y Zhai… - International Journal of …, 2022 - mdpi.com
The purpose of this study was to investigate the anti-fatigue effect of natural Lycium
barbarum polysaccharide (LBP) during exercise, develop a functional anti-fatigue …
barbarum polysaccharide (LBP) during exercise, develop a functional anti-fatigue …
Dapagliflozin protects heart function against type-4 cardiorenal syndrome through activation of PKM2/PP1/FUNDC1-dependent mitophagy
Y Shen, X Peng, H Ji, W Gong, H Zhu… - International Journal of …, 2023 - Elsevier
Dapagliflozin (DAPA) confers significant protection against heart and kidney diseases.
However, whether DAPA can alleviate type 4 cardiorenal syndrome (CRS-4)-related …
However, whether DAPA can alleviate type 4 cardiorenal syndrome (CRS-4)-related …
Macrophage‐Derived Extracellular Vesicles‐Coated Palladium Nanoformulations Modulate Inflammatory and Immune Homeostasis for Targeting Therapy of …
J Cheng, Y Zhang, L Ma, W Du, Q Zhang… - Advanced …, 2023 - Wiley Online Library
Ulcerative colitis (UC) is a chronic inflammatory bowel disease mainly involving the colon
and rectum, which features recurrent mucosal inflammation. The excessive production of …
and rectum, which features recurrent mucosal inflammation. The excessive production of …
[HTML][HTML] Comprehensive analysis of FOXM1 immune infiltrates, m6a, glycolysis and ceRNA network in human hepatocellular carcinoma
Z Xu, C Pei, H Cheng, K Song, J Yang, Y Li… - Frontiers in …, 2023 - frontiersin.org
Background Forkhead box M1 (FOXM1) is a member of the Forkhead box (Fox) transcription
factor family. It regulates cell mitosis, cell proliferation, and genome stability. However, the …
factor family. It regulates cell mitosis, cell proliferation, and genome stability. However, the …
Pyruvate kinase M2 regulates kidney fibrosis through pericyte glycolysis during the progression from acute kidney injury to chronic kidney disease
Y Chen, X Bai, J Chen, M Huang, Q Hong… - Cell …, 2024 - Wiley Online Library
We aimed to investigate the role of renal pericyte pyruvate kinase M2 (PKM2) in the
progression of acute kidney injury (AKI) to chronic kidney disease (CKD). The role of PKM2 …
progression of acute kidney injury (AKI) to chronic kidney disease (CKD). The role of PKM2 …
[HTML][HTML] SMYD3 promotes aerobic glycolysis in diffuse large B-cell lymphoma via H3K4me3-mediated PKM2 transcription
T Tian, J Li, D Shi, Y Zeng, B Yu, X Li, P Wei… - Cell Death & …, 2022 - nature.com
Genetic abnormalities in histone methyltransferases (HMTs) frequently occur in diffuse large
B-cell lymphoma (DLBCL) and are related to its progression. SET and MYND domain …
B-cell lymphoma (DLBCL) and are related to its progression. SET and MYND domain …
[HTML][HTML] Druggable Metabolic Vulnerabilities are exposed and masked during progression to castration resistant prostate cancer
SYC Choi, CF Ribeiro, Y Wang, M Loda, SR Plymate… - Biomolecules, 2022 - mdpi.com
There is an urgent need for exploring new actionable targets other than androgen receptor
to improve outcome from lethal castration-resistant prostate cancer. Tumor metabolism has …
to improve outcome from lethal castration-resistant prostate cancer. Tumor metabolism has …