Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …

Aims: Ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-AKI) is characterized
by elevated levels of reactive oxygen species (ROS), mitochondrial dysfunction, and …

The demand for biomaterials that promote the repair, replacement, or restoration of hard and
soft tissues continues to grow as the population ages. Traditionally, smart biomaterials have …

Mitochondrial dysfunction is a key feature of injury to numerous tissues and stem cell aging.
Although the tissue regenerative role of mesenchymal stem cell (MSC)-derived extracellular …

Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in
tissue engineering and regenerative medicine. However, recent evidence suggests that the …

Mesenchymal stem cells (MSCs) have been widely applied to regenerative medicine owing
to their multiple differentiation, self‐renewal, and immunomodulatory abilities. Exosomes are …

The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …

The extracellular matrix (ECM) harbours various signals to control cellular functions and the
materiality of tissues. Most efforts to synthetically reconstitute the matrix by biomaterial …

The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …