Vitiligo is an acquired immune-mediated disorder of pigmentation clinically characterized by
well-defined depigmented or chalk-white macules and patches on the skin. The prevalence …

Background and Aims The diverse inflammatory response found in the liver of patients with
autoimmune hepatitis (AIH) is well established, but identification of potentially pathogenic …

Vitiligo is a T cell–mediated inflammatory skin disorder characterized by the loss of
epidermal melanocytes. However, the contribution of melanocytes to the physiopathology of …

Autoimmune diseases often present with cutaneous symptoms that contribute to dysfunction,
disfigurement, and in many cases, reduced quality-of-life. Unfortunately, treatment options …

Vitiligo is a disease of the skin characterized by the appearance of white spots. Significant
progress has been made in understanding vitiligo pathogenesis over the past 30 years, but …

Vitiligo is an asymptomatic but cosmetically disfiguring disorder that results in the formation
of depigmented patches on skin and/or mucosae. Vitiligo can be segmental or non …

Granzymes are a family of small (∼ 32 kDa) serine proteases with a range of substrate
specificities that are stored in, and released from, the cytoplasmic secretory vesicles …

Vitiligo is a chronic inflammatory skin disease leading to the loss of epidermal melanocytes.
To date, treatment options for vitiligo patients are limited, lack sustained efficacy, and are …

Background A number of studies have shown the relationship between the pathogenesis of
psoriasis and skin resident memory T (T RM) cells. Objective To investigate the cytokine …

Autoimmune diseases are driven by either T cells or antibodies reacting specifically to 1 or
more self-antigens. Although a number of self-antigens associated with skin diseases have …