[HTML][HTML] Vitiligo-like lesions and COVID-19: case report and review of vaccination-and infection-associated vitiligo

L Macca, L Peterle, M Ceccarelli, Y Ingrasciotta… - Vaccines, 2022 - mdpi.com
Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been
described in the literature. Herein, we presented a case of new-onset vitiligo that occurred …

Vitiligo as a skin memory disease: the need for early intervention with immunomodulating agents and a maintenance therapy to target resident memory T cells

K Boniface, J Seneschal - Experimental dermatology, 2019 - Wiley Online Library
The understanding of the immune mechanisms of vitiligo has profoundly improved over the
past years. The recent discovery of a new population of antigen‐experienced memory T …

Resident memory T cells in non-lesional skin and healed lesions of patients with chronic inflammatory diseases: appearances can be deceptive

L Migayron, R Merhi, J Seneschal… - Journal of Allergy and …, 2023 - Elsevier
Tissue-resident memory T (T RM) cells serve as a first line of defense in peripheral tissues to
protect the organism against foreign pathogens. However, autoreactive T RM cells are …

[HTML][HTML] A mouse model of vitiligo based on endogenous auto-reactive CD8+ T cell targeting skin melanocyte

D Chen, Z Xu, J Cui, T Chen - Cell Regeneration, 2022 - Springer
Vitiligo is the most common human skin depigmenting disorder. It is mediated by
endogenous autoreactive CD8+ T cells that destruct skin melanocytes. This disease has an …

[HTML][HTML] HSP70iQ435A-encoding DNA repigments vitiligo lesions in Sinclair swine

SW Henning, MF Fernandez, JP Mahon, R Duff… - Journal of Investigative …, 2018 - Elsevier
Human HSP70i Q435A carries a single amino-acid modification within the dendritic cell
activating region and tolerizes dendritic cells in vitro. The underlying DNA was used to …

T‐cell positioning by chemokines in autoimmune skin diseases

JM Richmond, JP Strassner, KI Essien… - Immunological …, 2019 - Wiley Online Library
Autoimmune skin diseases are complex processes in which autoreactive cells must navigate
through the skin tissue to find their targets. Regulatory T cells in the skin help to mitigate …

Targeted multi-omic analysis of human skin tissue identifies alterations of conventional and unconventional T cells associated with burn injury

DR Labuz, G Lewis, ID Fleming, CM Thompson, Y Zhai… - Elife, 2023 - elifesciences.org
Burn injuries are a leading cause of unintentional injury, associated with a dysfunctional
immune response and an increased risk of infections. Despite this, little is known about the …

Elevated serum level of interleukin‐15 in vitiligo patients and its correlation with disease severity but not activity

MA Atwa, SMM Ali, N Youssef… - Journal of Cosmetic …, 2021 - Wiley Online Library
Background Vitiligo is a common acquired disorder of depigmentation. Its pathogenesis
entails a T helper (Th) 1‐cytotoxic T (cT) lymphocytes mediated autoimmune melanocyte …

Systemic CXCL10 is a predictive biomarker of vitiligo lesional skin infiltration, PUVA, NB-UVB and corticosteroid treatment response and outcome

M El-Domyati, WH El-Din, AF Rezk… - Archives of …, 2022 - Springer
Vitiligo is an acquired pigmentary skin disorder that currently lacks standardized treatment
and validated biomarkers to objectively evaluate disease state or therapeutic response …

[HTML][HTML] Targeting the PD-1/PD-L1 axis in human vitiligo

M Willemsen, CJM Melief, MW Bekkenk… - Frontiers in …, 2020 - frontiersin.org
Autoreactive CD8+ T cells play a pivotal role in melanocyte destruction in autoimmune
vitiligo. Immunotherapy for melanoma often leads to autoimmune side-effects, among which …