Colorectal cancer (CRC) is one of malignant afflictions burdening people worldwide, mainly
caused by shortages of effective medical intervention and poorly mechanistic understanding …

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating
adaptive and maladaptive responses toward exogenous and endogenous signals …

Inflammation is considered to be a crucial factor in the development of chronic diseases,
eight of which were listed among the top ten causes of death worldwide in the World Health …

Alopecia areata (AA) is a chronic, immune‐mediated disease characterized by acute or
chronic non‐scarring hair loss, with a heterogeneity in clinical manifestations ranging from …

Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

Background & Aims We evaluated the efficacy of once-daily (QD) upadacitinib 45 mg, an
oral, reversible Janus kinase inhibitor, on early symptomatic improvement for ulcerative …

Nanoparticles are primarily taken up by immune cells after systemic administration. Thus,
they are considered an ideal drug delivery vehicle for immunomodulation. Because the …

Autoimmune and inflammatory diseases are common and diverse, and they can affect
nearly any organ system. Much of the pathogenesis of these diseases is related to …

The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

In recent years, the broadening understanding of the pathogenesis of atopic dermatitis (AD)
has led to the development of novel therapeutic molecules, that target core inflammatory …