Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair
B Marchetti, C Tirolo, F L'Episcopo, S Caniglia… - Aging cell, 2020 - Wiley Online Library
A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …
[HTML][HTML] Current understanding of the mesenchymal stem cell-derived exosomes in cancer and aging
M Muralikumar, SM Jain, H Ganesan, AK Duttaroy… - Biotechnology …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are being widely researched upon for several years with
translational application in regenerative medicine. Many studies acknowledged trophic …
translational application in regenerative medicine. Many studies acknowledged trophic …
[HTML][HTML] Applications of human organoids in the personalized treatment for digestive diseases
Q Wang, F Guo, Y Jin, Y Ma - Signal Transduction and Targeted …, 2022 - nature.com
Digestive system diseases arise primarily through the interplay of genetic and environmental
influences; there is an urgent need in elucidating the pathogenic mechanisms of these …
influences; there is an urgent need in elucidating the pathogenic mechanisms of these …
[HTML][HTML] Astragaloside IV alleviates intestinal barrier dysfunction via the AKT-GSK3β-β-catenin pathway in peritoneal dialysis
J He, M Wang, L Yang, H Xin, F Bian, G Jiang… - Frontiers in …, 2022 - frontiersin.org
Background and aims: Long-term peritoneal dialysis (PD) causes intestinal dysfunction,
including constipation, diarrhea, or enteric peritonitis. However, the etiology and …
including constipation, diarrhea, or enteric peritonitis. However, the etiology and …
Wnt signalling inhibitors potently drive trans-differentiation potential of mesenchymal stem cells towards neuronal lineage
Purpose To date to repair and restore the neurons in neurodegenerative disorders,
numerous approaches are addressed, but the retaining activities of those cells were not well …
numerous approaches are addressed, but the retaining activities of those cells were not well …
[HTML][HTML] Notch2 Regulates the Function of Bovine Follicular Granulosa Cells via the Wnt2/β-Catenin Signaling Pathway
W Dang, Y Ren, Q Chen, M He, E Kebreab, D Wang… - Animals, 2024 - mdpi.com
Simple Summary This study investigated the crosstalk between the Wnt/β-catenin and Notch
signaling pathways and the roles of these pathways in apoptosis, cell cycle progression …
signaling pathways and the roles of these pathways in apoptosis, cell cycle progression …
Tumor suppressor microRNAs in gastrointestinal cancers: a mini-review
G Jothimani, M Bhatiya, S Pathak… - Recent Advances in …, 2022 - ingentaconnect.com
Background: Gastrointestinal (GI) cancer is associated with a group of cancers affecting the
organs in the GI tract, with a high incidence and mortality rate. This type of cancer …
organs in the GI tract, with a high incidence and mortality rate. This type of cancer …
Bench to bedside: New therapeutic approaches with extracellular vesicles and engineered biomaterials for targeting therapeutic resistance of cancer stem cells
Cancer has recently been the second leading cause of death worldwide, trailing only
cardiovascular disease. Cancer stem cells (CSCs), represented as tumor-initiating cells …
cardiovascular disease. Cancer stem cells (CSCs), represented as tumor-initiating cells …
[HTML][HTML] Expanding the Etiology of Oculo–Auriculo–Vertebral Spectrum: A Novel Interstitial Microdeletion at 1p36
M García-Castro, T Martinez-Merino, N Puente… - International Journal of …, 2022 - mdpi.com
The etiology of oculo–auriculo–vertebral spectrum (OAVS) is not well established. About half
of patients show a positive family history. The etiology of familiar cases is unclear but …
of patients show a positive family history. The etiology of familiar cases is unclear but …
Regulating the Wnt/β‐catenin Signaling Pathway Promotes Repigmentation in Vitiligo Using Fire Needle Therapy
YL Xu, GM Sun, JM Zhang, YH Ma, GZ Li… - Dermatologic …, 2024 - Wiley Online Library
Background. Vitiligo is a dermatological disorder characterized by the depletion of
melanocytes. The key to its treatment lies in the promotion of melanin regeneration. The …
melanocytes. The key to its treatment lies in the promotion of melanin regeneration. The …