Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair

B Marchetti, C Tirolo, F L'Episcopo, S Caniglia… - Aging cell, 2020 - Wiley Online Library
A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

[HTML][HTML] Current understanding of the mesenchymal stem cell-derived exosomes in cancer and aging

M Muralikumar, SM Jain, H Ganesan, AK Duttaroy… - Biotechnology …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are being widely researched upon for several years with
translational application in regenerative medicine. Many studies acknowledged trophic …

[HTML][HTML] Applications of human organoids in the personalized treatment for digestive diseases

Q Wang, F Guo, Y Jin, Y Ma - Signal Transduction and Targeted …, 2022 - nature.com
Digestive system diseases arise primarily through the interplay of genetic and environmental
influences; there is an urgent need in elucidating the pathogenic mechanisms of these …

[HTML][HTML] Astragaloside IV alleviates intestinal barrier dysfunction via the AKT-GSK3β-β-catenin pathway in peritoneal dialysis

J He, M Wang, L Yang, H Xin, F Bian, G Jiang… - Frontiers in …, 2022 - frontiersin.org
Background and aims: Long-term peritoneal dialysis (PD) causes intestinal dysfunction,
including constipation, diarrhea, or enteric peritonitis. However, the etiology and …

Wnt signalling inhibitors potently drive trans-differentiation potential of mesenchymal stem cells towards neuronal lineage

A Banerjee, P Rowlo, G Jothimani, AK Duttaroy… - Journal of Medical and …, 2022 - Springer
Purpose To date to repair and restore the neurons in neurodegenerative disorders,
numerous approaches are addressed, but the retaining activities of those cells were not well …

[HTML][HTML] Notch2 Regulates the Function of Bovine Follicular Granulosa Cells via the Wnt2/β-Catenin Signaling Pathway

W Dang, Y Ren, Q Chen, M He, E Kebreab, D Wang… - Animals, 2024 - mdpi.com
Simple Summary This study investigated the crosstalk between the Wnt/β-catenin and Notch
signaling pathways and the roles of these pathways in apoptosis, cell cycle progression …

Tumor suppressor microRNAs in gastrointestinal cancers: a mini-review

G Jothimani, M Bhatiya, S Pathak… - Recent Advances in …, 2022 - ingentaconnect.com
Background: Gastrointestinal (GI) cancer is associated with a group of cancers affecting the
organs in the GI tract, with a high incidence and mortality rate. This type of cancer …

Bench to bedside: New therapeutic approaches with extracellular vesicles and engineered biomaterials for targeting therapeutic resistance of cancer stem cells

G Ingavle, M Das - ACS Biomaterials Science & Engineering, 2022 - ACS Publications
Cancer has recently been the second leading cause of death worldwide, trailing only
cardiovascular disease. Cancer stem cells (CSCs), represented as tumor-initiating cells …

[HTML][HTML] Expanding the Etiology of Oculo–Auriculo–Vertebral Spectrum: A Novel Interstitial Microdeletion at 1p36

M García-Castro, T Martinez-Merino, N Puente… - International Journal of …, 2022 - mdpi.com
The etiology of oculo–auriculo–vertebral spectrum (OAVS) is not well established. About half
of patients show a positive family history. The etiology of familiar cases is unclear but …

Regulating the Wnt/β‐catenin Signaling Pathway Promotes Repigmentation in Vitiligo Using Fire Needle Therapy

YL Xu, GM Sun, JM Zhang, YH Ma, GZ Li… - Dermatologic …, 2024 - Wiley Online Library
Background. Vitiligo is a dermatological disorder characterized by the depletion of
melanocytes. The key to its treatment lies in the promotion of melanin regeneration. The …