[HTML][HTML] Alzheimer's disease current therapies, novel drug delivery systems and future directions for better disease management

B Singh, CM Day, S Abdella, S Garg - Journal of Controlled Release, 2024 - Elsevier
Abstract Alzheimer's disease (AD), is a neurodegenerative disorder that escalates with time,
exerting a significant impact on physical and mental health and leading to death. The …

[HTML][HTML] Intranasal polymeric and lipid-based nanocarriers for CNS drug delivery

R Maher, A Moreno-Borrallo, D Jindal, BT Mai… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is currently focused on the design and development of nanocarriers that
enhance drug delivery to the brain to address unmet clinical needs for treating …

Use of poly lactic-co-glycolic acid nano and micro particles in the delivery of drugs modulating different phases of inflammation

C Puricelli, CL Gigliotti, I Stoppa, S Sacchetti… - Pharmaceutics, 2023 - mdpi.com
Chronic inflammation contributes to the pathogenesis of many diseases, including
apparently unrelated conditions such as metabolic disorders, cardiovascular diseases …

Bone tissue and the nervous system: what do they have in common?

A Minoia, L Dalle Carbonare, JC Schwamborn… - Cells, 2022 - mdpi.com
Degenerative diseases affecting bone tissues and the brain represent important problems
with high socio-economic impact. Certain bone diseases, such as osteoporosis, are …

Mechanistic insights and emerging therapeutic stratagems for Alzheimer's disease

K Rajendran, UM Krishnan - Ageing Research Reviews, 2024 - Elsevier
Abstract Alzheimer's disease (AD), a multi-factorial neurodegenerative disorder has affected
over 30 million individuals globally and these numbers are expected to increase in the …

A perspective on PLGA encapsulated radio agents

FZ Biber Muftuler - Journal of Radioanalytical and Nuclear Chemistry, 2023 - Springer
Today, it is well known that radioactive nano systems, particularly radioactive nano particles
(NPs) based on polymeric NPs possess great advantages on nuclear imaging and/or …

Pharmacokinetics and Pharmacodynamics of Novel Drug Delivery Systems: From Basic Concepts to Applications: A Machine-Generated Literature Overview

SA Gharat - 2024 - books.google.com
The science of drug delivery has witnessed remarkable advancements in the everevolving
era of pharmaceuticals and healthcare that promise to revolutionize clinical therapeutics …

Nose-to-Brain Drug Delivery Strategies for the Treatment of Neurological Disorders

D Bhatane, A Alexander - Drug Delivery Strategies in Neurological …, 2024 - Springer
Neurological disorders such as Alzheimer's disease, Parkinson's disease, epilepsy, glioma,
depression, and anxiety are seriously affecting humans across the globe. Currently, FDA …

Pharmacokinetics and Pharmacodynamics of Nanocarriers and Novel Drug Delivery Systems

SA Gharat, MM Momin, T Khan - … of Novel Drug Delivery Systems: From …, 2024 - Springer
The pharmacokinetics of nanocarriers and novel drug delivery systems play a pivotal role in
optimizing the delivery and therapeutic efficacy of drugs. These systems, such as liposomes …