The production of recombinant pharmaceutical proteins in plants

JKC Ma, PMW Drake, P Christou - Nature reviews genetics, 2003 - nature.com
Imagine a world in which any protein, either naturally occurring or designed by man, could
be produced safely, inexpensively and in almost unlimited quantities using only simple …

Plant cell cultures for the production of recombinant proteins

S Hellwig, J Drossard, RM Twyman, R Fischer - Nature biotechnology, 2004 - nature.com
The use of whole plants for the synthesis of recombinant proteins has received a great deal
of attention recently because of advantages in economy, scalability and safety compared …

Plant cell cultures: chemical factories of secondary metabolites

SR Rao, GA Ravishankar - Biotechnology advances, 2002 - Elsevier
This review deals with the production of high-value secondary metabolites including
pharmaceuticals and food additives through plant cell cultures, shoot cultures, root cultures …

[图书][B] Introduction to plant biotechnology (3/e)

HS Chawla - 2011 - taylorfrancis.com
This book has been written to meet the needs of students for biotechnology courses at
various levels of undergraduate and graduate studies. This book covers all the important …

Molecular farming of pharmaceutical proteins

R Fischer, N Emans - Transgenic research, 2000 - Springer
Molecular farming is the production of pharmaceutically important and commercially
valuable proteins in plants. Its purpose is to provide a safe and inexpensive means for the …

Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures

J Xu, X Ge, MC Dolan - Biotechnology advances, 2011 - Elsevier
“Molecular farming” in plants with significant advantages in cost and safety is touted as a
promising platform for the production of complex pharmaceutical proteins. While whole-plant …

Genetically modified plants and human health

S Key, JKC Ma, PMW Drake - Journal of the Royal Society of …, 2008 - journals.sagepub.com
Genetically modified (or GM) plants have attracted a large amount of media attention in
recent years and continue to do so. Despite this, the general public remains largely unaware …

RIBOSOME-INACTIVATING PROTEINS: A Plant Perspective

K Nielsen, RS Boston - Annual review of plant biology, 2001 - annualreviews.org
▪ Abstract Ribosome-inactivating proteins (RIPs) are toxic N-glycosidases that depurinate
the universally conserved α-sarcin loop of large rRNAs. This depurination inactivates the …

Foreign protein production in plant tissue cultures

PM Doran - Current Opinion in Biotechnology, 2000 - Elsevier
Foreign proteins synthesised by plants are now in the marketplace, and clinical trials for
plant-derived therapeutic proteins are underway. Economic analysis of plant production …

A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes

L Zeitlin, SS Olmsted, TR Moench, MS Co… - Nature …, 1998 - nature.com
The ability to produce monoclonal antibodies (Mabs) in plants offers the opportunity for the
development of an inexpensive method of mucosal immunoprotection against sexually …