Developmental programming and transgenerational transmission of obesity
MH Vickers - Annals of Nutrition and Metabolism, 2014 - karger.com
The global obesity pandemic is often causally linked to marked changes in diet and lifestyle,
namely marked increases in dietary intakes of high-energy diets and concomitant reductions …
namely marked increases in dietary intakes of high-energy diets and concomitant reductions …
[HTML][HTML] Oxidative stress in mouse sperm impairs embryo development, fetal growth and alters adiposity and glucose regulation in female offspring
Paternal health cues are able to program the health of the next generation however the
mechanism for this transmission is unknown. Reactive oxygen species (ROS) are increased …
mechanism for this transmission is unknown. Reactive oxygen species (ROS) are increased …
Preconception maternal and paternal exposure to persistent organic pollutants and birth size: the LIFE study
Background: Persistent organic pollutants (POPs) are developmental toxicants, but the
impact of both maternal and paternal exposures on offspring birth size is largely unexplored …
impact of both maternal and paternal exposures on offspring birth size is largely unexplored …
Germ cell origins of posttraumatic stress disorder risk: the transgenerational impact of parental stress experience
AB Rodgers, TL Bale - Biological psychiatry, 2015 - Elsevier
Altered stress reactivity is a predominant feature of posttraumatic stress disorder (PTSD) and
may reflect disease vulnerability, increasing the probability that an individual will develop …
may reflect disease vulnerability, increasing the probability that an individual will develop …
Epigenetics in fish gametes and early embryo
The spermatozoa and oocyte are very specialized cells which possess the unique ability to
fuse and to produce an embryo. This embryo will develop into a mature organism capable of …
fuse and to produce an embryo. This embryo will develop into a mature organism capable of …
The emerging role of microRNAs and nutrition in modulating health and disease
SA Ross, CD Davis - Annual review of nutrition, 2014 - annualreviews.org
Understanding the molecular mechanisms that inform how diet and dietary supplements
influence health and disease is an active research area. One such mechanism concerns the …
influence health and disease is an active research area. One such mechanism concerns the …
Father's environment before conception and asthma risk in his children: a multi-generation analysis of the Respiratory Health In Northern Europe study
C Svanes, J Koplin, SM Skulstad… - International journal …, 2017 - academic.oup.com
Background: Whereas it is generally accepted that maternal environment plays a key role in
child health, emerging evidence suggests that paternal environment before conception also …
child health, emerging evidence suggests that paternal environment before conception also …
Effects of obesity and diabetes on the epigenetic modification of mammalian gametes
XH Ou, CC Zhu, SC Sun - Journal of cellular physiology, 2019 - Wiley Online Library
Obesity and diabetes are closely associated with numerous reproductive disorders,
including termination of ovulation, irregular menstruation, low fertility, abortion, and risky …
including termination of ovulation, irregular menstruation, low fertility, abortion, and risky …
The influence of seminal plasma on offspring development and health
HL Morgan, AJ Watkins - Seminars in cell & developmental biology, 2020 - Elsevier
The concept that a father's wellbeing at the time of conception influences the development
and long-term health of his offspring is now well established. However, the mechanisms …
and long-term health of his offspring is now well established. However, the mechanisms …
Paternal high‐fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring
We previously showed that paternal high‐fat diet (HFD) consumption programs β‐cell
dysfunction in female rat offspring, together with transcriptome alterations in islets. Here we …
dysfunction in female rat offspring, together with transcriptome alterations in islets. Here we …