Hydrogel-based controlled drug delivery for cancer treatment: a review

Z Sun, C Song, C Wang, Y Hu, J Wu - Molecular pharmaceutics, 2019 - ACS Publications
As an emerging drug carrier, hydrogels have been widely used for tumor drug delivery. A
hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

Engineered exosomes for targeted co-delivery of miR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer

G Liang, Y Zhu, DJ Ali, T Tian, H Xu, K Si, B Sun… - Journal of …, 2020 - Springer
Abstract Background 5-Fluorouracil (5-FU) has been commonly prescribed for patients with
colorectal cancer (CRC), but resistance to 5-FU is one of the main reasons for failure in …

Polymeric nanocarriers of drug delivery systems in cancer therapy

N Avramović, B Mandić, A Savić-Radojević, T Simić - Pharmaceutics, 2020 - mdpi.com
Conventional chemotherapy is the most common therapeutic method for treating cancer by
the application of small toxic molecules thatinteract with DNA and causecell death …

Recent advances of cocktail chemotherapy by combination drug delivery systems

Q Hu, W Sun, C Wang, Z Gu - Advanced drug delivery reviews, 2016 - Elsevier
Combination chemotherapy is widely exploited for enhanced cancer treatment in the clinic.
However, the traditional cocktail administration of combination regimens often suffers from …

Liposome-based drug co-delivery systems in cancer cells

SZ Vahed, R Salehi, S Davaran, S Sharifi - Materials Science and …, 2017 - Elsevier
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

miRNA nanotherapeutics for cancer

A Ganju, S Khan, BB Hafeez, SW Behrman… - Drug discovery today, 2017 - Elsevier
Highlights•MicroRNAs play a major role in cancer.•Several clinical trials with microRNA are
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …

Nanomedicine of synergistic drug combinations for cancer therapy–Strategies and perspectives

RX Zhang, HL Wong, HY Xue, JY Eoh… - Journal of Controlled …, 2016 - Elsevier
Nanomedicine of synergistic drug combinations has shown increasing significance in
cancer therapy due to its promise in providing superior therapeutic benefits to the current …

Combinational strategy for high-performance cancer chemotherapy

SY Qin, YJ Cheng, Q Lei, AQ Zhang, XZ Zhang - Biomaterials, 2018 - Elsevier
The clinical outcomes of conventional mono-chemotherapy of cancers are usually far from
satisfactory due to some issues such as tumor heterogeneity and resistance to …

Targeting miRNAs and other non-coding RNAs as a therapeutic approach: an update

E Bayraktar, R Bayraktar, H Oztatlici… - Non-coding RNA, 2023 - mdpi.com
Since the discovery of the first microRNAs (miRNAs, miRs), the understanding of miRNA
biology has expanded substantially. miRNAs are involved and described as master …