Nutritional niches of cancer therapy-induced senescent cells
À Llop-Hernández, S Verdura, E Cuyàs, JA Menendez - Nutrients, 2022 - mdpi.com
Therapy-induced senescence (TIS) is a state of stable proliferative arrest of both normal and
neoplastic cells that is triggered by exposure to anticancer treatments. TIS cells acquire a …
neoplastic cells that is triggered by exposure to anticancer treatments. TIS cells acquire a …
Radiation-induced cellular senescence reduces susceptibility of glioblastoma cells to oncolytic vaccinia virus
QT Storozynsky, X Han, S Komant, KC Agopsowicz… - Cancers, 2023 - mdpi.com
Simple Summary Novel therapeutic approaches combining oncolytic virus (OV) therapy and
radiotherapy are being investigated to improve treatment for glioblastoma (GBM). However …
radiotherapy are being investigated to improve treatment for glioblastoma (GBM). However …
Cancer associated fibroblasts and senescent thyroid cells in the invasive front of thyroid carcinoma
E Minna, S Brich, K Todoerti, S Pilotti, P Collini… - Cancers, 2020 - mdpi.com
Thyroid carcinoma (TC) comprises several histotypes with different aggressiveness, from
well (papillary carcinoma, PTC) to less differentiated forms (poorly differentiated and …
well (papillary carcinoma, PTC) to less differentiated forms (poorly differentiated and …
Mechanisms of cancer stem cell senescence: Current understanding and future perspectives
DY Zhang, MJ Monteiro, JP Liu… - Clinical and Experimental …, 2021 - Wiley Online Library
Cancer stem cells (CSCs) are a small population of heterogeneous tumor cells with the
capacity of self‐renewal and aberrant differentiation for immortality and divergent lineages of …
capacity of self‐renewal and aberrant differentiation for immortality and divergent lineages of …
[HTML][HTML] Matrix-driven changes in metabolism support cytoskeletal activity to promote cell migration
The microenvironment provides both active and passive mechanical cues that regulate cell
morphology, adhesion, migration, and metabolism. Although the cellular response to those …
morphology, adhesion, migration, and metabolism. Although the cellular response to those …
Tactics of cancer invasion: solitary and collective invasion
T Nagai, T Ishikawa, Y Minami… - The journal of …, 2020 - academic.oup.com
Much attention has been paid on the mechanism of cancer invasion from the viewpoint of
the behaviour of individual cancer cells. On the other hand, histopathological analyses of …
the behaviour of individual cancer cells. On the other hand, histopathological analyses of …
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer
X Zheng, Z Liu, J Zhong, L Zhou, J Chen, L Zheng, Z Li… - Oncogene, 2022 - nature.com
Transcription dysregulation is a salient characteristic of bladder cancer (BC), but no
appropriate therapeutic target for it has been established. Here, we found that …
appropriate therapeutic target for it has been established. Here, we found that …
Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol
JY Kim, KH Cho, BY Jeong, CG Park… - Experimental & Molecular …, 2020 - nature.com
Rab coupling protein (RCP) is upregulated in head and neck squamous cell carcinoma
(HNSCC) and is correlated with the progression and survival of patients. However, the role …
(HNSCC) and is correlated with the progression and survival of patients. However, the role …
ABCA1-Mediated EMT Promotes Papillary Thyroid Cancer Malignancy through the ERK/Fra-1/ZEB1 Pathway
JH Park, JK Myung, SJ Lee, H Kim, S Kim, SB Lee… - Cells, 2023 - mdpi.com
Papillary thyroid cancer (PTC) is the most prevalent histological type of thyroid cancer (TC)
worldwide. Although tumor metastasis occurs in regional lymph nodes, distant metastasis …
worldwide. Although tumor metastasis occurs in regional lymph nodes, distant metastasis …
Cellular senescence: from anti-cancer weapon to anti-aging target
L Yuan, PB Alexander, XF Wang - Science China Life Sciences, 2020 - Springer
Cellular senescence (CS) is a state of stable cell cycle arrest characterized by the
production and secretion of inflammatory molecules. Early studies described oncogene …
production and secretion of inflammatory molecules. Early studies described oncogene …