The effect of acute, chronic, and prenatal ethanol exposure on insulin sensitivity

JW Ting, WW Lautt - Pharmacology & therapeutics, 2006 - Elsevier
Ethanol has been considered as a lifestyle factor that may influence the risk of type 2
diabetes mellitus. In healthy adults, acute ethanol consumption results in insulin resistance …

[图书][B] Why fetal alcohol abuse syndrome?

EL Abel, EL Abel - 1998 - Springer
About three days after a human egg is fertilized, it passes through the fallopian tunnel and
reaches the uterus, where it spends about four days floating in the uterus's fluids, after which …

Placental transfer of selected substances of abuse

BB Little, TT VanBeveren - Seminars in perinatology, 1996 - Elsevier
The placenta was classically considered a barrier, but in 1957 this notion was shattered.
This organ is only a selective filter and metabolic site. In this review, the placental transfer of …

Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse

JR Araujo, P Gonçalves, F Martel - Journal of biochemistry, 2008 - academic.oup.com
The aim of this work was to investigate the putative modulation of glucose uptake in
trophoblast cells by several dietary compounds and by drugs of abuse. For this, the acute …

Functional connectivity and metabolic alterations in medial prefrontal cortex in a rat model of fetal alcohol spectrum disorder: a resting-state functional magnetic …

S Tang, S Xu, J Waddell, W Zhu, RP Gullapalli… - Developmental …, 2019 - karger.com
Prenatal ethanol exposure alters brain structure, functional connectivity, and behavior in
humans and rats. Behavioral changes include deficits in executive function, which requires …

Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line …

E Keating, C Lemos, P Gonçalves, F Martel - The Journal of Nutritional …, 2008 - Elsevier
Folic acid (FA) is a vitamin that acts as a coenzyme in the biosynthesis of purine and
pyrimidine precursors of nucleic acids, which are critically important during pregnancy. Our …

Neurobehavioral consequences of intermittent prenatal exposure to high concentrations of toluene

HE Jones, RL Balster - Neurotoxicology and teratology, 1997 - Elsevier
The effects of several concentrations of toluene on physical and behavioral development
were examined in CD-1 mice prenatally exposed during the last week of gestation. Pregnant …

Acute ethanol exposure in pregnancy alters the insulin-like growth factor axis of fetal and maternal sheep

KL Gatford, PA Dalitz, ML Cock… - American Journal of …, 2007 - journals.physiology.org
Maternal ethanol intake during pregnancy impairs fetal growth, but mechanisms are not
clearly defined. Reduced IGF abundance or bioavailability in the fetus and/or mother may …

Alcohol-induced alterations in maternal uterine endothelial proteome: a quantitative iTRAQ mass spectrometric approach

J Ramadoss, RR Magness - Reproductive toxicology, 2012 - Elsevier
OBJECTIVE: To quantitate alcohol-induced alterations in the maternal uterine endothelial
proteome utilizing iTRAQ-based mass spectrometry. STUDY DESIGN: Uterine artery …

Maternal ethanol exposure is associated with decreased plasma zinc and increased fetal abnormalities in normal but not metallothionein‐null mice

LC Carey, P Coyle, JC Philcox… - Alcoholism: Clinical and …, 2000 - Wiley Online Library
Background: Ethanol profoundly affects fetal development, and this is proposed to be due
primarily to a transient fetal zinc (Zn) deficiency that arises from the binding of Zn by …