Primary liver cancer is one of the most common malignant tumours worldwide; it caused
approximately 830,000 deaths in 2020. Hepatocellular carcinoma (HCC) is the most …

Radiation therapy (RT) is widely used in cancer care strategies. Its effectiveness relies
mainly on its ability to cause lethal damage to the DNA of cancer cells. However, some …

Hepatocellular carcinoma is one of the most frequent malignant tumors worldwide: Portal
vein tumor thrombosis (PVTT) occurs in about 35%-50% of patients and represents a strong …

Advanced hepatocellular carcinoma (HCC) has a very low resectable rate. This meta-
analysis aimed to compare efficacy of three combination strategies in treatment of advanced …

Purpose To determine the maximally tolerated dose of sorafenib delivered before, during,
and after stereotactic body radiation therapy (SBRT) in hepatocellular carinoma (HCC) …

Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide; its incidence
is increasing in the United States. Depending on disease extent and underlying liver status …

Background Hepatocellular carcinoma (HCC) is one of the main reasons for malignancy-
related death. Portal vein tumor thrombosis (PVTT) is the most common form of …

Stereotactic Body Radiation Therapy (SBRT) is an emerging effective treatment for
hepatocellular carcinoma (HCC) associated with acceptable rates of toxicity in appropriately …

Background Limited effective intervention for advanced hepatocellular carcinoma (HCC) is
available. This study aimed to investigate the potential clinical utility of apatinib, a highly …

ERK1 and ERK2 (ERKs), two extracellular regulated kinases (ERK1/2), are evolutionary-
conserved and ubiquitous serine-threonine kinases involved in regulating cell signalling in …