Reactive oxygen species and gastric carcinogenesis: The complex interaction between Helicobacter pylori and host

S Wu, Y Chen, Z Chen, F Wei, Q Zhou, P Li… - Helicobacter, 2023 - Wiley Online Library
Helicobacter pylori (H. pylori) is a highly successful human pathogen that colonizes stomach
in around 50% of the global population. The colonization of bacterium induces an …

[HTML][HTML] A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment

R Kinoshita-Daitoku, K Kiga, M Miyakoshi… - Nature …, 2021 - nature.com
Long-term infection of the stomach with Helicobacter pylori can cause gastric cancer.
However, the mechanisms by which the bacteria adapt to the stomach environment are …

GO system, a DNA repair pathway to cope with oxidative damage

AV Endutkin, DO Zharkov - Molecular Biology, 2021 - Springer
The GO system is part of the DNA base excision repair pathway and is required for the error-
free repair of 8-oxoguanine (oxoG), one of the most common oxidative DNA lesions. Due to …

Antibiotic-induced ROS-mediated Fur allosterism contributes to Helicobacter pylori resistance by inhibiting arsR activation of mutS and mutY

J Xue, W Li, Y Zhao, L Wang, P Cheng… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
The increasing antibiotic resistance of Helicobacter pylori primarily driven by genetic
mutations poses a significant clinical challenge. Although previous research has suggested …

細菌感染症におけるRNA の機能解明と抗菌治療への応用

氣駕恒太朗 - 日本細菌学雑誌, 2022 - jstage.jst.go.jp
抄録 セントラルドグマ (DNA から RNA が転写されて, タンパク質ができる) という分子生物学の
中心的な概念において,「RNA は DNA からタンパク質を合成するための遺伝情報の仲介役にすぎ …

[HTML][HTML] ピロリ菌の持続感染メカニズム

三室仁美 - Journal of Japanese Biochemical Society, 2023 - seikagaku.jbsoc.or.jp
Helicobacter pylori (H. pylori, ピロリ菌) は, 乳幼児期に経口的に体内に入ると,
何十年にもわたり胃粘膜に付着性の持続感染を成立させ, 萎縮性胃炎, 胃潰瘍 …