The WNT/β-catenin (CTNNB1) pathway is commonly activated in the carcinogenic process.
Cross-talks between the WNT and cyclooxygenase-2 (COX-2 or PTGS2)/prostaglandin …

Biallelic germ‐line variants of the 8‐hydroxyguanine repair gene MYH have been
associated with multiple colorectal adenomas that display somatic G: C→ T: A transversions …

In this paper we introduce a clustering algorithm capable of simultaneously factorizing two
distinct gene expression datasets with the aim of uncovering gene regulatory programs that …

AIM: To investigate aberrant DNA methylation of CpG islands and subsequent low-or high-
level DNA microsatellite instability (MSI) which is assumed to drive colon carcinogenesis …

Results: In 22 patients with HPS, 209 polyps were detected, including 27 with normal
histology, 116 hyperplastic polyps, 42 SSAs, and 24 adenomas. Among patients assigned to …

Background There is uncertainty on the benefit of adjuvant chemotherapy in patients with
stage II colorectal cancers. The aim of this study is to investigate the combined role of …

Background Despite their pivotal roles in colorectal carcinogenesis, the interrelationship and
prognostic significance of beta-catenin alterations and microsatellite instability (MSI) in …

Microsatellite instability (MSI) is associated with defective DNA mismatch repair in various
human malignancies. Using a unique fluorescent technique, we have observed two distinct …

Context.—Carcinomas of the appendix are usually well-differentiated mucinous
adenocarcinomas that tend to produce pseudomyxoma peritonei and do not show …

Background: Colorectal cancers (CRCs) may be categorised according to the degree of
microsatellite instability (MSI) exhibited, as MSI-high (MSI-H), MSI-low (MSI-L), or …