Seeing (and using) the light: recent developments in bioluminescence technology

AC Love, JA Prescher - Cell Chemical Biology, 2020 - cell.com
Bioluminescence has long been used to image biological processes in vivo. This technology
features luciferase enzymes and luciferin small molecules that produce visible light …

Leaving the dark side? Insights into the evolution of luciferases

J Delroisse, L Duchatelet, P Flammang… - Frontiers in Marine …, 2021 - frontiersin.org
Bioluminescence—ie, the emission of visible light by living organisms—is defined as a
biochemical reaction involving, at least, a luciferin substrate, an oxygen derivative, and a …

Multicomponent bioluminescence imaging with a π-extended luciferin

Z Yao, BS Zhang, RC Steinhardt, JH Mills… - Journal of the …, 2020 - ACS Publications
Bioluminescence imaging with luciferase-luciferin pairs is commonly used for monitoring
biological processes in cells and whole organisms. Traditional bioluminescent probes are …

[HTML][HTML] Understanding the complete bioluminescence cycle from a multiscale computational perspective: A review

YJ Liu - Journal of Photochemistry and Photobiology C …, 2022 - Elsevier
Bioluminescence (BL) is an amazing natural phenomenon whose visible light is produced
by living organisms. BL phenomenon is quite pervasive and has been observed in 17 phyla …

Building Biological Flashlights: Orthogonal Luciferases and Luciferins for in Vivo Imaging

SJ Williams, JA Prescher - Accounts of chemical research, 2019 - ACS Publications
Conspectus Bioluminescence is widely used for real-time imaging in living organisms. This
technology features a light-emitting reaction between enzymes (luciferases) and small …

Recent progress in expanding the chemiluminescent toolbox for bioimaging

K Suzuki, T Nagai - Current Opinion in Biotechnology, 2017 - Elsevier
Highlights•The color palette of bright luminescent proteins harnessing FRET is
introduced.•The most recent near-infrared emitting luciferins are introduced.•Ca 2+, ATP …

Selected least studied but not forgotten bioluminescent systems

Y Oba, CV Stevani, AG Oliveira… - Photochemistry and …, 2017 - Wiley Online Library
Bioluminescence is a form of chemiluminescence generated by luminous organisms.
Luminous taxa have currently been reported from about 800 genera and probably over 10 …

Enzymatic promiscuity and the evolution of bioluminescence

ST Adams Jr, SC Miller - The FEBS journal, 2020 - Wiley Online Library
Bioluminescence occurs when an enzyme, known as a luciferase, oxidizes a small‐
molecule substrate, known as a luciferin. Nature has evolved multiple distinct luciferases …

Metabolic engineering and mechanical investigation of enhanced plant autoluminescence

P Zheng, J Ge, J Ji, J Zhong, H Chen… - Plant Biotechnology …, 2023 - Wiley Online Library
The fungal bioluminescence pathway (FBP) was identified from glowing fungi, which
releases self‐sustained visible green luminescence. However, weak bioluminescence limits …

Dynamical insights into the decomposition of 1, 2-dioxetane

M Vacher, A Brakestad, HO Karlsson… - Journal of Chemical …, 2017 - ACS Publications
Chemiluminescence in 1, 2-dioxetane occurs through a thermally activated decomposition
reaction into two formaldehyde molecules. Both ground-state and nonadiabatic dynamics …