Agents for fluorescence-guided glioma surgery: a systematic review of preclinical and clinical results

JT Senders, IS Muskens, R Schnoor, AV Karhade… - Acta …, 2017 - Springer
Background Fluorescence-guided surgery (FGS) is a technique used to enhance
visualization of tumor margins in order to increase the extent of tumor resection in glioma …

Intraoperative fluorescence imaging for personalized brain tumor resection: current state and future directions

E Belykh, NL Martirosyan, K Yagmurlu, EJ Miller… - Frontiers in …, 2016 - frontiersin.org
Introduction Fluorescence-guided surgery is one of the rapidly emerging methods of surgical
“theranostics.” In this review, we summarize current fluorescence techniques used in …

Phototheranostics: active targeting of orthotopic glioma using biomimetic proteolipid nanoparticles

Y Jia, X Wang, D Hu, P Wang, Q Liu, X Zhang, J Jiang… - ACS …, 2018 - ACS Publications
Advances in phototheranostics revolutionized glioma intraoperative fluorescence imaging
and phototherapy. However, the lack of desired active targeting agents for crossing the …

Quantitative in vivo cell-surface receptor imaging in oncology: kinetic modeling and paired-agent principles from nuclear medicine and optical imaging

KM Tichauer, Y Wang, BW Pogue… - Physics in Medicine & …, 2015 - iopscience.iop.org
The development of methods to accurately quantify cell-surface receptors in living tissues
would have a seminal impact in oncology. For example, accurate measures of receptor …

[HTML][HTML] High precision imaging of microscopic spread of glioblastoma with a targeted ultrasensitive SERRS molecular imaging probe

R Huang, S Harmsen, JM Samii, H Karabeber… - Theranostics, 2016 - ncbi.nlm.nih.gov
The dismal prognosis of patients with malignant brain tumors such as glioblastoma
multiforme (GBM) is attributed mostly to their diffuse growth pattern and early microscopic …

Hypoxia-Responsive Lipid–Polymer Nanoparticle-Combined Imaging-Guided Surgery and Multitherapy Strategies for Glioma

H Xu, Y Han, G Zhao, L Zhang, Z Zhao… - … Applied Materials & …, 2020 - ACS Publications
Glioma is the most prevalent type of malignant brain tumor and is usually very aggressive.
Because of the high invasiveness and aggressive proliferative growth of glioma, it is difficult …

Manganese-doped carbon dots for magnetic resonance/optical dual-modal imaging of tiny brain glioma

Z Ji, P Ai, C Shao, T Wang, C Yan, L Ye… - … Biomaterials Science & …, 2018 - ACS Publications
Brain gliomas are life-threatening diseases with low survival rates. Early detection and
accurate intraoperative location of brain gliomas is vital to improving the prognosis. Herein …

Visualization technologies for 5-ALA-based fluorescence-guided surgeries

L Wei, DW Roberts, N Sanai, JTC Liu - Journal of Neuro-oncology, 2019 - Springer
Abstract Introduction 5-ALA-based fluorescence-guided surgery has been shown to be a
safe and effective method to improve intraoperative visualization and resection of malignant …

Optical principles of fluorescence-guided brain tumor surgery: a practical primer for the neurosurgeon

DY Zhang, S Singhal, JYK Lee - Neurosurgery, 2019 - journals.lww.com
Fluorescence-guided surgery is a rapidly growing field that has produced some of the most
important innovations in surgical oncology in the past decade. These intraoperative imaging …

Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection

KI Swanson, PA Clark, RR Zhang, IK Kandela… - …, 2015 - journals.lww.com
BACKGROUND: 5-Aminolevulinic acid (5-ALA)-induced tumor fluorescence aids brain
tumor resections but is not approved for routine use in the United States. We developed and …