[PDF][PDF] Investigating the expression changes of genes involved in the biosynthesis of androgens in prostate adenocarcinoma and benign prostatic hyperplasia

GGV Zaghard, M Haghi, M Ghiamirad… - Int. J. Bio-Inorg. Hybr …, 2022 - journals.iau.ir
Prostate cancer (PCa) is the second most frequently diagnosed malignancy in men
worldwide. Androgens are critical for normal prostate development and function, as well as …

[PDF][PDF] Better Understanding the Timing Of Androgen Deprivation (TOAD) Trial Outcomes: Impacts of Prior ADT

MS Theresa Devasia, MD Megan Caram, BKHMD MS… - 2022 - scholar.archive.org
5. Health Services Research & Development Center for Clinical Management Research, VA
Ann Arbor Healthcare System, Ann Arbor, MI, USA 6. Department of Radiation Oncology …

[PDF][PDF] Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) with a highly selective inhibitor for the treatment of prostate cancer

K Yuan, Z Li, W Kuang, X Wang, M Ji, J Li, W Min… - 2021 - scholar.archive.org
Prostate cancer (PCa) is one of the most prevalent cancers in men worldwide, and hormonal
therapy plays a key role in the treatment of PCa. However, the inevitable drug resistance of …

[PDF][PDF] Single-cell ATAC and RNA sequencing reveal pre-existing and persistent subpopulations of cells associated with relapse of prostate cancer

S Taavitsainen, N Engedal, S Cao, F Handle… - 2021 - lirias.kuleuven.be
Prostate cancer is heterogeneous and patients would bene t from methods that stratify those
who are likely to respond to systemic therapy. We employed single-cell assays for …

Better Understanding the Timing Of Androgen Deprivation Trial Outcomes: Impacts of Prior Androgen Deprivation Therapy

KD Stensland, T Devasia, MEV Caram… - JNCI Cancer …, 2022 - academic.oup.com
Abstract Background The Timing Of Androgen Deprivation (TOAD) trial found an overall
survival benefit for immediate vs delayed androgen deprivation therapy (ADT) for prostate …

Models of Tumor Progression in Prostate Cancer

W Azeem, Y Hua, KH Kalland, X Ke, JR Olsen… - Biomarkers of the Tumor …, 2022 - Springer
Human prostate cancer is initiated in a benign prostate epithelial cell which gains the
potential to progress to invasive and metastatic disease. The exact cell of origin of prostate …