Functional urological disorders: a sensitized defence response in the bladder–gut–brain axis
C Leue, J Kruimel, D Vrijens, A Masclee… - Nature Reviews …, 2017 - nature.com
Functional urological and gastrointestinal disorders are interrelated and characterized by a
chronic course and considerable treatment resistance. Urological disorders associated with …
chronic course and considerable treatment resistance. Urological disorders associated with …
Diagnosis and treatment of the overactive bladder
AJ Wein - Urology, 2003 - Elsevier
Overactive bladder syndrome (OAB) is a symptomatic diagnosis based on the presence of
urgency, with or without urge incontinence, and usually accompanied by frequency and …
urgency, with or without urge incontinence, and usually accompanied by frequency and …
BDNF promotes activation of astrocytes and microglia contributing to neuroinflammation and mechanical allodynia in cyclophosphamide-induced cystitis
H Ding, J Chen, M Su, Z Lin, H Zhan, F Yang… - Journal of …, 2020 - Springer
Background Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) often grieve
over a low quality of life brought about by chronic pain. In our previous studies, we …
over a low quality of life brought about by chronic pain. In our previous studies, we …
Persistence and adherence of medications for chronic overactive bladder/urinary incontinence in the California Medicaid program
OBJECTIVES: To investigate persistence and adherence of medication treatment in chronic
overactive bladder/urinary incontinence (OAB/UI) patients, and to evaluate OAB/UI-related …
overactive bladder/urinary incontinence (OAB/UI) patients, and to evaluate OAB/UI-related …
Solifenacin appears effective and well tolerated in patients with symptomatic idiopathic detrusor overactivity in a placebo‐and tolterodine‐controlled phase 2 dose …
CR Chapple, P Arano, J Bosch, D De Ridder… - BJU …, 2004 - Wiley Online Library
Early results using two new agents to treat urinary incontinence are published. The use of
Ro 115–1240 in women with stress urinary incontinence is presented, with encouraging …
Ro 115–1240 in women with stress urinary incontinence is presented, with encouraging …
Social stress-induced bladder dysfunction: potential role of corticotropin-releasing factor
SK Wood, MA Baez, S Bhatnagar… - American Journal of …, 2009 - journals.physiology.org
Psychological stress can impact on visceral function with pathological consequences,
although the mechanisms underlying this are poorly understood. Here we demonstrate that …
although the mechanisms underlying this are poorly understood. Here we demonstrate that …
The bladder–brain connection: putative role of corticotropin-releasing factor
The coordination of pelvic visceral activity with appropriate elimination behaviors is a
complex task that requires reciprocal communication between the brain and pelvic organs …
complex task that requires reciprocal communication between the brain and pelvic organs …
Linguistic validation of the N‐QOL (ICIQ), OAB‐q (ICIQ), PPBC, OAB‐S and ICIQ‐MLUTSsex questionnaires in 16 languages
S McKown, L Abraham, K Coyne… - … journal of clinical …, 2010 - Wiley Online Library
Objective: Overactive bladder (OAB) is a highly prevalent condition with a negative impact
on both health‐related quality of life and sexual functioning. We aimed to create and validate …
on both health‐related quality of life and sexual functioning. We aimed to create and validate …
Impact of overactive bladder on the brain: central sequelae of a visceral pathology
E Rickenbacher, MA Baez, L Hale… - Proceedings of the …, 2008 - National Acad Sciences
Neural circuits that allow for reciprocal communication between the brain and viscera are
critical for coordinating behavior with visceral activity. At the same time, these circuits are …
critical for coordinating behavior with visceral activity. At the same time, these circuits are …
A comparison of the efficacy of darifenacin alone vs. darifenacin plus a Behavioural Modification Programme upon the symptoms of overactive bladder
MB Chancellor, F Kianifard, E Beamer… - … journal of clinical …, 2008 - Wiley Online Library
Purpose: This study assessed the benefit of adding behavioural modification to darifenacin
treatment for overactive bladder (OAB). Materials and methods: The ABLE trial was a …
treatment for overactive bladder (OAB). Materials and methods: The ABLE trial was a …