[HTML][HTML] Stress management: death receptor signalling and cross-talks with the unfolded protein response in cancer
E Lafont - Cancers, 2020 - mdpi.com
Throughout tumour progression, tumour cells are exposed to various intense cellular stress
conditions owing to intrinsic and extrinsic cues, to which some cells are remarkably able to …
conditions owing to intrinsic and extrinsic cues, to which some cells are remarkably able to …
[HTML][HTML] Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening
M Voss, M Lettau, O Janssen - BMC immunology, 2009 - Springer
Background-Fas ligand is a cytotoxic effector molecule of T and NK cells which is
characterized by an intracellular N-terminal polyproline region that serves as a docking site …
characterized by an intracellular N-terminal polyproline region that serves as a docking site …
[HTML][HTML] Differential inhibition of signal peptide peptidase family members by established γ-secretase inhibitors
Y Ran, GZ Ladd, C Ceballos-Diaz, JI Jung… - PLoS …, 2015 - journals.plos.org
The signal peptide peptidases (SPPs) are biomedically important proteases implicated as
therapeutic targets for hepatitis C (human SPP,(hSPP)), plasmodium (Plasmodium SPP …
therapeutic targets for hepatitis C (human SPP,(hSPP)), plasmodium (Plasmodium SPP …
Intramembrane proteolysis within lysosomes
B Schröder, P Saftig - Ageing Research Reviews, 2016 - Elsevier
Regulated intramembrane proteolysis is of pivotal importance in a diverse set of
developmental and physiological processes. Altered intramembrane substrate turnover may …
developmental and physiological processes. Altered intramembrane substrate turnover may …
The intramembrane protease SPPL2A is critical for tooth enamel formation
ALJJ Bronckers, N Gueneli… - Journal of Bone and …, 2013 - academic.oup.com
Intramembrane proteases are critically involved in signal transduction and membrane
protein turnover. Signal‐peptide‐peptidase‐like 2a (SPPL2A), a presenilin‐homologue …
protein turnover. Signal‐peptide‐peptidase‐like 2a (SPPL2A), a presenilin‐homologue …
Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes
A Linkermann, C Gelhaus, M Lettau, J Qian… - … et Biophysica Acta (BBA …, 2009 - Elsevier
Pombe Cdc15 homology (PCH) family proteins are regarded as key elements for linking
membrane-associated processes to cytoskeletal elements and thus play a major role in exo …
membrane-associated processes to cytoskeletal elements and thus play a major role in exo …
[HTML][HTML] Fas ligand enhances malignant behavior of tumor cells through interaction with Met, hepatocyte growth factor receptor, in lipid rafts
HC Lin, PY Lai, Y Lin, JY Huang, BC Yang - Journal of Biological Chemistry, 2012 - ASBMB
Many late-stage cancer cells express Fas ligand (FasL) and show high malignancy with
metastatic potential. We report here a novel signaling mechanism for FasL that hijacks the …
metastatic potential. We report here a novel signaling mechanism for FasL that hijacks the …
Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma
F Yasunari, MA Bustos, C Sung-Nam… - Cell Death and …, 2022 - search.proquest.com
Soluble forms of receptors play distinctive roles in modulating signal-transduction pathways.
Soluble CD74 (sCD74) has been identified in sera of inflammatory diseases and implicated …
Soluble CD74 (sCD74) has been identified in sera of inflammatory diseases and implicated …
[HTML][HTML] No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells
J Nys, CR Smulski, A Tardivel, L Willen, C Kowalczyk… - PLoS …, 2013 - journals.plos.org
Myeloid cells express the TNF family ligands BAFF/BLyS and APRIL, which exert their
effects on B cells at different stages of differentiation via the receptors BAFFR, TACI …
effects on B cells at different stages of differentiation via the receptors BAFFR, TACI …
[HTML][HTML] Impairment of Fas-ligand–caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death
XA Glukhova, JA Trizna, OV Proussakova… - Cell death & …, 2018 - nature.com
Fas-ligand/CD178 belongs to the TNF family proteins and can induce apoptosis through
death receptor Fas/CD95. The important requirement for Fas-ligand-dependent cell death …
death receptor Fas/CD95. The important requirement for Fas-ligand-dependent cell death …