Polycystic ovarian syndrome: Current scenario and future insights

S Kulkarni, K Gupta, P Ratre, PK Mishra, Y Singh… - Drug Discovery …, 2023 - Elsevier
Polycystic ovarian syndrome (PCOS) prevails in approximately 33% of females of
reproductive age globally. Although the root cause of the disease is unknown, attempts are …

[HTML][HTML] Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement in human granulosa cells through transcriptome …

M Zanjirband, R Hodayi, Z Safaeinejad… - Scientific Reports, 2023 - nature.com
The polycystic ovarian syndrome (PCOS) is closely associated with enhanced apoptosis of
granulosa cells, which have a vital role in maturation of oocytes. p53 plays a critical role in …

[HTML][HTML] Induced Pluripotent Stem Cells as a Possible Approach for Exploring the Pathophysiology of Polycystic Ovary Syndrome (PCOS)

M Khatun, K Lundin, F Naillat, L Loog… - Stem cell reviews and …, 2024 - Springer
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine condition among women
with pleiotropic sequelae possessing reproductive, metabolic, and psychological …

Sine cosine algorithm-based feature selection for improved machine learning models in polycystic ovary syndrome diagnosis

IS Rajput, S Tyagi, A Gupta, V Jain - Multimedia Tools and Applications, 2024 - Springer
Abstract Polycystic Ovary Syndrome (PCOS) is a hormonal state that affects women within
the reproductive age group. Early and accurate diagnosis of medical conditions is crucial for …

Role of inflammation, oxidative stress, and angiogenesis in polycystic ovary syndrome (PCOS): Current perspectives

A Wal, B Dash, V Jaiswal, D Gupta… - … inflammation, and oxidative …, 2024 - Elsevier
Polycystic ovarian syndrome (PCOS) is characterized as an endocrine and metabolic
disorder mainly due to hormonal imbalance. It generally affects women at the reproductive …

血必净注射液对心脏骤停/心肺复苏后大鼠神经功能及生存情况的影响机制

黄德庆, 高玉广, 张元侃, 王政林, 邓海霞… - 中国 …, 2024 - journal.china-pharmacy.com
目的基于S-亚硝基谷胱甘肽还原酶(GSNOR)/S-亚硝基谷胱甘肽(GSNO) 途径探讨血必净注射液
对大鼠心脏骤停(CA)/心肺复苏(CPR) 后神经功能及生存情况影响的潜在机制 …

[PDF][PDF] 高雄激素诱导小鼠颗粒细胞氧化应激与炎症的研究

翟怡, 庞艳莉 - 中国生育健康杂志 - cjrh.bjmu.edu.cn
目的探究高雄激素对颗粒细胞基因表达的广泛影响, 为多囊卵巢综合征(PCOS)
局部高雄的分子机制和干预靶点研究提供参考. 方法通过获取小鼠颗粒细胞, 体外添加DHEA …

Transcriptomic Analysis of the Effects Exerted by Curcumin on Dihydrotestosterone-Induced Ovarian Granulosa Cells

D Chen, Q Yu, S Sheng, L Cai, J Zheng, Y Zhang… - papers.ssrn.com
Hyperandrogenism is a leading cause of developmental retardation in ovarian granulosa
cells. Previous studies have indicated that curcumin significantly improves follicular …