Pre-eclampsia
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …
Liquid Biopsy Based on Cell-Free DNA and RNA
C Loy, L Ahmann, I De Vlaminck… - Annual Review of …, 2024 - annualreviews.org
This review delves into the rapidly evolving landscape of liquid biopsy technologies based
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …
Cis P-tau is a central circulating and placental etiologic driver and therapeutic target of preeclampsia
Preeclampsia (PE) is the leading cause of maternal and fetal mortality globally and may
trigger dementia later in life in mothers and their offspring. However, the etiological drivers …
trigger dementia later in life in mothers and their offspring. However, the etiological drivers …
Profiling of repetitive RNA sequences in the blood plasma of patients with cancer
Liquid biopsies provide a means for the profiling of cell-free RNAs secreted by cells
throughout the body. Although well-annotated coding and non-coding transcripts in blood …
throughout the body. Although well-annotated coding and non-coding transcripts in blood …
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
A well-functioning placenta is essential for fetal and maternal health throughout pregnancy.
Using placental weight as a proxy for placental growth, we report genome-wide association …
Using placental weight as a proxy for placental growth, we report genome-wide association …
Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors
TP Schrank, A Kothari, WH Weir… - Proceedings of the …, 2023 - National Acad Sciences
We analyzed transcriptional data from 104 HPV+ (Human papillomavirus) HNSCC (head
and neck squamous cell carcinoma) tumors together with two publicly available sources to …
and neck squamous cell carcinoma) tumors together with two publicly available sources to …
Current challenges and best practices for cell-free long RNA biomarker discovery
The analysis of biomarkers in biological fluids, also known as liquid biopsies, is seen with
great potential to diagnose complex diseases such as cancer with a high sensitivity and …
great potential to diagnose complex diseases such as cancer with a high sensitivity and …
Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease
BN Radford, X Zhao, T Glazer, M Eaton… - Nature …, 2023 - nature.com
Placental abnormalities have been sporadically implicated as a source of developmental
heart defects. Yet it remains unknown how often the placenta is at the root of congenital …
heart defects. Yet it remains unknown how often the placenta is at the root of congenital …
Delivery technologies for women's health applications
The treatment of women's health-related conditions, including reproductive tract and
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …
[HTML][HTML] Apicobasal RNA asymmetries regulate cell fate in the early mouse embryo
The spatial sorting of RNA transcripts is fundamental for the refinement of gene expression
to distinct subcellular regions. Although, in non-mammalian early embryogenesis …
to distinct subcellular regions. Although, in non-mammalian early embryogenesis …