Alpha-2 agonists, such as xylazine, clonidine, romifidine, detomidine, medetomidine, and
dexmedetomidine, are potent analgesic drugs that also induce physiologic and behavioral …

Objective To review the literature with regard to the use of different intravenous agents as
supplements to inhalational anaesthesia in horses. The Part 2 of this review will focus in the …

The enzyme catechol-O-methyltransferase (COMT) has been shown to play a critical role in
pain perception by regulating levels of epinephrine (Epi) and norepinephrine (NE). Although …

Several species of Bauhinia are used in traditional medicine for the treatment of
gastrointestinal diseases, diabetes, and inflammation, among other conditions. The aim of …

It is generally accepted that the development of gastric mucosal injury and protection is a
consequence of an imbalance between the existing aggressive and defensive factors in the …

The use of clonidine as a primary and adjuvant analgesic is well-documented. It is known
that imidazoline and α 2-adrenoceptors are involved in clonidine antinociception. Clonidine …

Alteration of the oxidative stress of hepatocellular carcinoma (HCC) cells can influence the
expressions of genes favored angiogenesis. Quinone reductase 2 which can activate …

Imidazoline receptors (IRs) have been recognized as promising targets in the treatment of
numerous diseases; and moxonidine and rilmenidine, agonists of I 1-IRs, are widely used as …

Doktori munkám során az imidazolin receptor (IR) ligandok gasztrointesztinális (GI) traktusra
kifejtett hatásait részletezem különböző állatmodellek (alkoholos fekély modell, kémiai úton …

Receptory są to wyspecjalizowane białka na powierzchni błony komórkowej lub we wnętrzu
komórki, do których mogą przyłączać się ligandy o określonej budowie. Umożliwiają …