The far-reaching scope of neuroinflammation after traumatic brain injury
DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …
of clinical investigations and popular press coverage of athletes and veterans with single or …
Cooling for newborns with hypoxic ischaemic encephalopathy
SE Jacobs, M Berg, R Hunt… - Cochrane database …, 2013 - cochranelibrary.com
Background Newborn animal studies and pilot studies in humans suggest that mild
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …
[HTML][HTML] Energetic trade-offs and hypometabolic states promote disease tolerance
Host defenses against pathogens are energetically expensive, leading ecological
immunologists to postulate that they might participate in energetic trade-offs with other …
immunologists to postulate that they might participate in energetic trade-offs with other …
Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia
SA Bernard, TW Gray, MD Buist… - New England journal …, 2002 - Mass Medical Soc
Background Cardiac arrest outside the hospital is common and has a poor outcome. Studies
in laboratory animals suggest that hypothermia induced shortly after the restoration of …
in laboratory animals suggest that hypothermia induced shortly after the restoration of …
The ICH score: a simple, reliable grading scale for intracerebral hemorrhage
JC Hemphill III, DC Bonovich, L Besmertis, GT Manley… - stroke, 2001 - Am Heart Assoc
Background and Purpose—Intracerebral hemorrhage (ICH) constitutes 10% to 15% of all
strokes and remains without a treatment of proven benefit. Despite several existing outcome …
strokes and remains without a treatment of proven benefit. Despite several existing outcome …
Critical care management of severe traumatic brain injury in adults
Traumatic brain injury (TBI) is a major medical and socio-economic problem, and is the
leading cause of death in children and young adults. The critical care management of …
leading cause of death in children and young adults. The critical care management of …
[PDF][PDF] Integrated physiological mechanisms of exercise performance, adaptation, and maladaptation to heat stress
This article emphasizes significant recent advances regarding heat stress and its impact on
exercise performance, adaptations, fluid electrolyte imbalances, and pathophysiology …
exercise performance, adaptations, fluid electrolyte imbalances, and pathophysiology …
Heat stroke
LR Leon, A Bouchama - Comprehensive Physiology, 2011 - Wiley Online Library
Heat stroke is a life‐threatening condition clinically diagnosed as a severe elevation in body
temperature with central nervous system dysfunction that often includes combativeness …
temperature with central nervous system dysfunction that often includes combativeness …
Very early hypothermia induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial
GL Clifton, A Valadka, D Zygun, CS Coffey… - The Lancet …, 2011 - thelancet.com
Background The inconsistent effect of hypothermia treatment on severe brain injury in
previous trials might be because hypothermia was induced too late after injury. We aimed to …
previous trials might be because hypothermia was induced too late after injury. We aimed to …
Lack of effect of induction of hypothermia after acute brain injury
GL Clifton, ER Miller, SC Choi, HS Levin… - … England Journal of …, 2001 - Mass Medical Soc
Background Induction of hypothermia in patients with brain injury was shown to improve
outcomes in small clinical studies, but the results were not definitive. To study this issue, we …
outcomes in small clinical studies, but the results were not definitive. To study this issue, we …