Alternative DNA repair pathways to handle complex DNA damage generated by oxidative stress and anticancer drugs
E Matta, U Aliyaskarova, AA Kuznetsova… - 2020 - books.rsc.org
249 origin of mutagenesis and cell lethality. 1, 2 DNA damage can be classified by its
nature: spontaneous versus induced; by its structure: bulky versus non-bulky, base versus …
nature: spontaneous versus induced; by its structure: bulky versus non-bulky, base versus …
[HTML][HTML] DNA Adductomic Analysis by Data-Independent Mass Spectrometry
J Guo, PW Villalta, RJ Turesky - 2018 - spectroscopyonline.com
A new type of analysis called “wide-selected ion monitoring (SIM)/MS2” scanning, is capable
of screening for a wide range of DNA adducts (chemical modifications to genomic DNA) …
of screening for a wide range of DNA adducts (chemical modifications to genomic DNA) …
Transferring Nucleic Acids to the Gas Phase
G Grégoire - Nucleic Acids in the Gas Phase, 2014 - Springer
During the past 30 years, tremendous efforts have been made to implement mass
spectrometry and spectroscopy technologies for the characterization of biomolecules in the …
spectrometry and spectroscopy technologies for the characterization of biomolecules in the …
[PDF][PDF] Oxidative Stress Levels in Buccal Cells Using MAWI Collection Tubes
SB Tabbouny, E Chamoun… - Journal of …, 2017 - researchgate.net
Abstract Background: Oxidative Stress (OS) is defined as an imbalance between oxidants
and antioxidants, in favor of oxidants, potentially leading to DNA damage. Benzo [a] pyrene …
and antioxidants, in favor of oxidants, potentially leading to DNA damage. Benzo [a] pyrene …
Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry for Detection of 5-Hydroxymethyluracil and 5-Formyluracil in DNA
Y Liu, J Wang - DNA Modification Detection Methods, 2022 - Springer
Hydroxymethyluracil (5hmU) and 5-formyluracil (5fU) are mutagenic and major oxidized
nucleobases in DNA that are derived from thymine (T) or 5-methylcytosine (5mC). 5hmU …
nucleobases in DNA that are derived from thymine (T) or 5-methylcytosine (5mC). 5hmU …
Quantification of DNA damage using mass spectrometry techniques
T Douki, JL Ravanat - Nucleic Acids in the Gas Phase, 2014 - Springer
The role of DNA in cells relies on its chemical structure. Unfortunately, a number of physical
and chemical agents may damage DNA, leading to modification of genetic information or to …
and chemical agents may damage DNA, leading to modification of genetic information or to …
[PDF][PDF] Current and Future Methodology for Quantitation and Site-Specific Mapping the Location of DNA Adducts. Toxics 2022, 10, 45
Formation of DNA adducts is a key event for a genotoxic mode of action, and their presence
is often used as a surrogate for mutation and increased cancer risk. Interest in DNA adducts …
is often used as a surrogate for mutation and increased cancer risk. Interest in DNA adducts …
1, 3-Butadiene-Induced DNA Damage: Ethnic Differences and Sources of Formation
CCJ Krueger - 2022 - search.proquest.com
Abstract In the United States, lung cancer is the leading cause of cancer-related deaths.
Cigarette smoking is a major risk factor for lung cancer development, with approximately …
Cigarette smoking is a major risk factor for lung cancer development, with approximately …