SARS‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells
S Lukassen, RL Chua, T Trefzer, NC Kahn… - The EMBO …, 2020 - embopress.org
The SARS‐CoV‐2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID‐19 …
public health and urgently demands for increasing our understanding of COVID‐19 …
The pivotal role of TMPRSS2 in coronavirus disease 2019 and prostate cancer
V Mollica, A Rizzo, F Massari - Future Oncology, 2020 - Taylor & Francis
The coronavirus disease 2019 (COVID-19) pandemic represents a public health emergency
of international proportions, which is having catastrophic consequences throughout the …
of international proportions, which is having catastrophic consequences throughout the …
Host cell targets for unconventional antivirals against RNA viruses
VC Roa-Linares, M Escudero-Flórez… - Viruses, 2023 - mdpi.com
The recent COVID-19 crisis has highlighted the importance of RNA-based viruses. The most
prominent members of this group are SARS-CoV-2 (coronavirus), HIV (human …
prominent members of this group are SARS-CoV-2 (coronavirus), HIV (human …
Personalizing oncolytic virotherapy for glioblastoma: in search of biomarkers for response
E Stavrakaki, CMF Dirven, MLM Lamfers - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most frequent and aggressive primary brain
tumor. Despite multimodal treatment, the prognosis of GBM patients remains very poor …
tumor. Despite multimodal treatment, the prognosis of GBM patients remains very poor …
A structure-informed atlas of human-virus interactions
G Lasso, SV Mayer, ER Winkelmann, T Chu, O Elliot… - Cell, 2019 - cell.com
While knowledge of protein-protein interactions (PPIs) is critical for understanding virus-host
relationships, limitations on the scalability of high-throughput methods have hampered their …
relationships, limitations on the scalability of high-throughput methods have hampered their …
SARS-CoV-2 receptor ACE2 and TMPRSS2 are predominantly expressed in a transient secretory cell type in subsegmental bronchial branches
S Lukassen, RL Chua, T Trefzer, NC Kahn… - BioRxiv, 2020 - biorxiv.org
The SARS-CoV-2 pandemic affecting the human respiratory system severely challenges
public health and urgently demands for increasing our understanding of COVID-19 …
public health and urgently demands for increasing our understanding of COVID-19 …
Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking
P Croisé, C Estay-Ahumada, S Gasman, S Ory - Small GTPases, 2014 - Taylor & Francis
Rho GTPases are well known regulators of the actin cytoskeleton that act by binding and
activating actin nucleators. They are therefore involved in many actin-based processes …
activating actin nucleators. They are therefore involved in many actin-based processes …
Small GTPase—A key role in host cell for Coronavirus infection and a potential target for Coronavirus vaccine adjuvant discovery
W Hou, S Wang, H Wu, L Xue, B Wang, S Wang… - Viruses, 2022 - mdpi.com
Small GTPases are signaling molecules in regulating key cellular processes (eg, cell
differentiation, proliferation, and motility) as well as subcellular events (eg, vesicle …
differentiation, proliferation, and motility) as well as subcellular events (eg, vesicle …
Transient inhibition of PI3Kδ enhances the therapeutic effect of intravenous delivery of oncolytic vaccinia virus
MS Ferguson, LSC Dunmall, R Gangeswaran… - Molecular Therapy, 2020 - cell.com
Tumor-targeting oncolytic viruses such as vaccinia virus (VV) are attractive cancer
therapeutic agents that act through multiple mechanisms to provoke both tumor lysis and …
therapeutic agents that act through multiple mechanisms to provoke both tumor lysis and …
Expression of angiotensin-converting enzyme 2 and proteases in COVID-19 patients: a potential role of cellular FURIN in the pathogenesis of SARS-CoV-2
KD Alsibai - Medical hypotheses, 2020 - Elsevier
Recently, a mini-review was published in the Medical Hypotheses journal by Usul Afsar
entitled 2019-nCoV-SARS-CoV-2 (COVID-19) infection: Cruciality of Furin and relevance …
entitled 2019-nCoV-SARS-CoV-2 (COVID-19) infection: Cruciality of Furin and relevance …