[HTML][HTML] Fixel-based analysis of diffusion MRI: methods, applications, challenges and opportunities

T Dhollander, A Clemente, M Singh, F Boonstra… - Neuroimage, 2021 - Elsevier
Diffusion MRI has provided the neuroimaging community with a powerful tool to acquire in-
vivo data sensitive to microstructural features of white matter, up to 3 orders of magnitude …

Multimodal brain and retinal imaging of dopaminergic degeneration in Parkinson disease

JY Lee, A Martin-Bastida, A Murueta-Goyena… - Nature Reviews …, 2022 - nature.com
Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …

Retinal optical coherence tomography features associated with incident and prevalent Parkinson disease

SK Wagner, D Romero-Bascones, M Cortina-Borja… - Neurology, 2023 - AAN Enterprises
Background and Objectives Cadaveric studies have shown disease-related
neurodegeneration and other morphological abnormalities in the retina of individuals with …

Dementia with Lewy bodies: Impact of co‐pathologies and implications for clinical trial design

JB Toledo, C Abdelnour, RS Weil… - Alzheimer's & …, 2023 - Wiley Online Library
Dementia with Lewy bodies (DLB) is clinically defined by the presence of visual
hallucinations, fluctuations, rapid eye movement (REM) sleep behavioral disorder, and …

Structural and functional changes in the retina in Parkinson's disease

JN Alves, BU Westner, A Højlund, RS Weil… - Journal of Neurology …, 2023 - jnnp.bmj.com
Parkinson's disease is caused by degeneration of dopaminergic neurons, originating in the
substantia nigra pars compacta and characterised by bradykinesia, rest tremor and rigidity …

Sensory loss and risk of dementia

M Lad, W Sedley, TD Griffiths - The Neuroscientist, 2024 - journals.sagepub.com
Sensory loss in olfaction, vision, and hearing is a risk factor for dementia, but the reasons for
this are unclear. This review presents the neurobiological evidence linking each sensory …

Neuroimaging and fluid biomarkers in Parkinson's disease in an era of targeted interventions

A Zarkali, GEC Thomas, H Zetterberg… - Nature …, 2024 - nature.com
A major challenge in Parkinson's disease is the variability in symptoms and rates of
progression, underpinned by heterogeneity of pathological processes. Biomarkers are …

Functional and structural brain network correlates of visual hallucinations in Lewy body dementia

R Mehraram, LR Peraza, NRE Murphy, RA Cromarty… - Brain, 2022 - academic.oup.com
Visual hallucinations are a common feature of Lewy body dementia. Previous studies have
shown that visual hallucinations are highly specific in differentiating Lewy body dementia …

Visual dysfunction is a better predictor than retinal thickness for dementia in Parkinson's disease

N Hannaway, A Zarkali, LA Leyland… - Journal of Neurology …, 2023 - jnnp.bmj.com
Background Dementia is a common and devastating symptom of Parkinson's disease (PD).
Visual function and retinal structure are both emerging as potentially predictive for dementia …

[HTML][HTML] Neurovascular coupling dysfunction of visual network organization in Parkinson's disease

T Li, T Liu, J Zhang, Y Ma, G Wang, D Suo, B Yang… - Neurobiology of …, 2023 - Elsevier
Parkinson's disease (PD) has been showed perfusion and neural activity alterations in
specific regions, such as the motor and visual networks; however, the clinical significance of …