[HTML][HTML] The interplay of hypoxic and mental stress: Implications for anxiety and depressive disorders

J Burtscher, M Niedermeier, K Hüfner… - Neuroscience & …, 2022 - Elsevier
Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

[HTML][HTML] Human adaptation to high altitude: a review of convergence between genomic and proteomic signatures

V Sharma, R Varshney, NK Sethy - Human Genomics, 2022 - Springer
Both genomics-and proteomics-based investigations have identified several essential
genes, proteins, and pathways that may facilitate human adaptive genotype/phenotype in a …

[HTML][HTML] The use of pulse oximetry in the assessment of acclimatization to high altitude

T Dünnwald, R Kienast, D Niederseer, M Burtscher - Sensors, 2021 - mdpi.com
Background: Finger pulse oximeters are widely used to monitor physiological responses to
high-altitude exposure, the progress of acclimatization, and/or the potential development of …

[HTML][HTML] Hypoxia conditioning for high-altitude pre-acclimatization

M Burtscher, GP Millet, J Burtscher - Journal of Science in Sport and …, 2022 - Springer
Purpose Main purposes of pre-acclimatization by hypoxia conditioning (HC) are the
prevention of high-altitude illnesses and maintenance of aerobic exercise performance …

[HTML][HTML] A comprehensive review of respiratory, autonomic and cardiovascular responses to intermittent hypoxia in humans

S Puri, G Panza, JH Mateika - Experimental neurology, 2021 - Elsevier
This review explores forms of respiratory and autonomic plasticity, and associated outcome
measures, that are initiated by exposure to intermittent hypoxia. The review focuses primarily …

[HTML][HTML] Intermittent hypoxia conditioning: a potential multi-organ protective therapeutic strategy

Q Zhang, W Zhao, S Li, Y Ding, Y Wang… - International journal of …, 2023 - ncbi.nlm.nih.gov
Severe hypoxia can induce a range of systemic disorders; however, surprising resilience
can be obtained through sublethal adaptation to hypoxia, a process termed as hypoxic …

Understanding the pathophysiological mechanisms of cardiometabolic complications in obstructive sleep apnoea: towards personalised treatment approaches

S Ryan, EP Cummins, R Farre… - European …, 2020 - Eur Respiratory Soc
In January 2019, a European Respiratory Society research seminar entitled “Targeting the
detrimental effects of sleep disturbances and disorders” was held in Dublin, Ireland. It …

[HTML][HTML] Effects of environmental and pathological hypoxia on male fertility

Z Li, S Wang, C Gong, Y Hu, J Liu, W Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
Male infertility is a widespread health problem affecting approximately 6%–8% of the male
population, and hypoxia may be a causative factor. In mammals, two types of hypoxia are …

[HTML][HTML] Moderate altitude exposure impacts host fasting blood glucose and serum metabolome by regulation of the intestinal flora

D Liu, X Gao, X Huang, Y Fan, YE Wang… - Science of the Total …, 2023 - Elsevier
Moderate altitude exposure has shown beneficial effects on diabetes incidence but the
underlying mechanisms are not understood. Our study aimed to investigate how the human …

Intermittent hypoxia: A call for harmonization in terminology

GS Panza, J Burtscher, F Zhao - Journal of Applied …, 2023 - journals.physiology.org
Mild intermittent hypoxia may be a potent novel strategy to improve cardiovascular function,
motor and cognitive function, and altitude acclimatization. However, there is still a stigma …