[HTML][HTML] The role of CXCL family members in different diseases

C Zhou, Y Gao, P Ding, T Wu, G Ji - Cell Death Discovery, 2023 - nature.com
Chemokines are a large family mediating a lot of biological behaviors including chemotaxis,
tumor growth, angiogenesis and so on. As one member of this family, CXC subfamily …

[HTML][HTML] Targeting members of the chemokine family as a novel approach to treating neuropathic pain

K Pawlik, J Mika - Molecules, 2023 - mdpi.com
Neuropathic pain is a debilitating condition that affects millions of people worldwide.
Numerous studies indicate that this type of pain is a chronic condition with a complex …

[HTML][HTML] The multifaceted role of the CXC chemokines and receptors signaling axes in ALS pathophysiology

V La Cognata, G Morello, M Guarnaccia… - Progress in …, 2024 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disease with complex
genetic basis and still no clear etiology. Multiple intertwined layers of immune system …

Low shear stress induces macrophage infiltration and aggravates aneurysm wall inflammation via CCL7/CCR1/TAK1/NF-κB axis

H Wei, G Wang, Q Tian, C Liu, W Han, J Wang, P He… - Cellular …, 2024 - Elsevier
Background This study aimed to elucidate the mechanism by which wall shear stress (WSS)
influences vascular walls, accounting for the susceptibility of intracranial aneurysms (IAs) to …

ACKR3 in olfactory glia cells shapes the immune defense of the olfactory mucosa

A Dietz, K Senf, EM Neuhaus - Glia, 2024 - Wiley Online Library
Barrier‐forming olfactory glia cells, termed sustentacular cells, play important roles for
immune defense of the olfactory mucosa, for example as entry sites for SARS‐CoV‐2 and …

CXCL1-CXCR2 axis mediates inflammatory response after sciatic nerve injury by regulating macrophage infiltration

S Jiang, W Li, M Song, J Liang, G Liu, Q Du… - Molecular …, 2024 - Elsevier
Macrophages play a crucial role in the inflammatory response following sciatic nerve injury.
Studies have demonstrated that CXC motif chemokine (CXCL) 1 recruit macrophages by …

An Overview of the Mechanisms Involved in Neuralgia

BW Zhang, H Dong, Z Wu, X Jiang… - Journal of Inflammation …, 2023 - Taylor & Francis
Neuralgia is a frequently occurring condition that causes chronic pain and burdens both
patients and their families. Earlier research indicated that anti-inflammatory treatment, which …

[HTML][HTML] Neuroprotective Effects of CXCR2 Antagonist SB332235 on Traumatic Brain Injury Through Suppressing NLRP3 Inflammasome

K Zhao, X Zhou, M Chen, L Gou, D Mei, C Gao… - Neurochemical …, 2024 - Springer
The inflammatory process mediated by nucleotide-binding oligomerization domain (NOD)-
like receptor family pyrin domain comprising 3 (NLRP3) inflammasome plays a predominant …

APOL1 Induces Pyroptosis of Fibroblasts Through NLRP3/Caspase-1/GSDMD Signaling Pathway in Ulcerative Colitis

F Zhu, S Li, Q Gu, N Xie, Y Wu - Journal of Inflammation Research, 2023 - Taylor & Francis
Background Pyroptosis is a form of proinfammatory gasdermin-mediated programmed cell
death. Abnormal infammation in the intestine is a critical risk factor for Ulcerative colitis (UC) …