Almost 60 years have passed since the initial discovery by Hubel and Wiesel that changes
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …

Psychosis Psychosis is a syndrome embedded in several disorders, including schizophrenia
and bipolar disorder with psychotic features. Dopamine and glutamate are implicated in the …

The ability of the adult mammalian brain to compensate for neuronal loss caused by injury or
disease is very limited. Transplantation aims to replace lost neurons, but the extent to which …

Synapses are well known as the main structures responsible for transmitting information
through the release and recognition of neurotransmitters by pre-and post-synaptic neurons …

Fascinating about classical major histocompatibility complex (MHC) molecules is their
polymorphism. The present study is a review and discussion of the fish MHC situation. The …

The neotenous, or delayed, development of primate neurons, particularly human ones, is
thought to underlie primate-specific abilities like cognition. We tested whether synaptic …

Microglia shape synaptic connections among neurons of the central nervous system (CNS)
during development and adulthood. In this review, the actions by which they facilitate …

Molecular chaperone Heat Shock Protein 70 (Hsp70) plays an important protective role in
various neurodegenerative disorders often associated with aging, but its activity and …

Redox biology and immune signaling play major roles in the body, including in brain
function. A rapidly growing literature also suggests that redox and immune abnormalities are …

Dynamic modification of synaptic connectivity in response to sensory experience is a vital
step in the refinement of brain circuits as they are established during development and …