The roles of MicroRNA in lung cancer

KL Wu, YM Tsai, CT Lien, PL Kuo, JY Hung - International journal of …, 2019 - mdpi.com
Lung cancer is the most devastating malignancy in the world. Beyond genetic research,
epigenomic studies—especially investigations of microRNAs—have grown rapidly in …

Exo-miRNAs as a new tool for liquid biopsy in lung cancer

O Fortunato, P Gasparini, M Boeri, G Sozzi - Cancers, 2019 - mdpi.com
Lung cancer is the predominant cause of cancer-related deaths. The high mortality rates are
mainly due to the lack of diagnosis before the cancer is at a late stage. Liquid biopsy is a …

Evaluation of saliva and plasma cytokine biomarkers in patients with oral squamous cell carcinoma

LT Lee, YK Wong, HY Hsiao, YW Wang… - International Journal of …, 2018 - Elsevier
The aim of this study was to investigate potential biomarkers in human saliva and plasma to
aid in the early diagnosis of oral squamous cell carcinoma (OSCC). Saliva and plasma …

The role of MicroRNAs in lung cancer: implications for diagnosis and therapy

P Naeli, F Yousefi, Y Ghasemi… - Current molecular …, 2020 - ingentaconnect.com
Lung cancer is the first cause of cancer death in the world due to its high prevalence,
aggressiveness, late diagnosis, lack of effective treatment and poor prognosis. It also shows …

Non-invasive biomarkers for early lung cancer detection

H Saman, A Raza, K Patil, S Uddin… - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer remains the first cause of cancer worldwide. The main reason
for this high rate of death from lung cancer is dissemination of the disease at the time of …

Design, synthesis, and evaluation of a new series of thiazole-based anticancer agents as potent Akt inhibitors

MD Altıntop, B Sever, G Akalın Çiftçi, A Özdemir - Molecules, 2018 - mdpi.com
In an attempt to develop potent anticancer agents targeting Akt, new thiazole derivatives (1–
10) were synthesized and investigated for their cytotoxic effects on A549 human lung …

Serum exosomal miR‐1269a serves as a diagnostic marker and plays an oncogenic role in non‐small cell lung cancer

X Wang, X Jiang, J Li, J Wang, H Binang, S Shi… - Thoracic …, 2020 - Wiley Online Library
Background Early diagnosis improves the prognosis for non‐small cell lung cancer
(NSCLC); therefore, there is a pressing need for effective diagnostic methods for NSCLC …

MicroRNA in lung cancer—a novel potential way for early diagnosis and therapy

M Frydrychowicz, Ł Kuszel, G Dworacki… - Journal of Applied …, 2023 - Springer
Lung cancer is the most common cause of cancer-related deaths in the world. One of the
reasons of poor prognosis and high mortality of lung cancer patients is the diagnosis of the …

Liquid biopsy for early detection of lung cancer

P Hofman - Current Opinion in Oncology, 2017 - journals.lww.com
Several potential circulating biomarkers for the early detection of lung cancer exist. When
coupled to thoracic imaging, these biomarkers must give diagnosis of a totally resectable …

[HTML][HTML] Distinct roles of miR-34 family members on suppression of lung squamous cell carcinoma

D Sun, Y Wu, S Zhang, Y Han, J Shen, W Zheng… - Biomedicine & …, 2021 - Elsevier
Abstract miR-34, whose mimic was used on phase I clinical trial, has been extensively
reported since its dysfunction in various cancers including non-small-cell lung cancer …