Atherosclerosis and abdominal aortic aneurysms (AAAs) are multifactorial and polygenic
diseases with known environmental and genetic risk factors that contribute toward disease …

There is a worldwide epidemic of cardiovascular diseases causing not only a public health
issue but also accounting for trillions of dollars of healthcare expenditure. Studies pertaining …

Introduction• Epigenetics explained‐Epigenetic alterations are reversible• Atherosclerosis•
Epigenetics and association with atherosclerosis• Epigenetic regulation of cell activity‐T …

Epigenetics refers to heritable changes in gene expression patterns not caused by an
altered nucleotide sequence, and includes non-coding RNAs and covalent modifications of …

BACKGROUND: Bronchial asthma is a chronic inflammatory disease resulting from complex
gene-environment interactions. Natural microbial exposure has been identified as an …

Periodontitis is an infectious, inflammatory disease that is associated with a complex
interplay between specific bacteria, host response, and environmental factors. Because of its …

People living with HIV face a high risk of mental illness, especially depression. We do not yet
know the precise neurobiological mechanisms underlying HIV-associated depression …

Aim: Delivery by C‐section (CS) has been associated with increased risk for allergy,
diabetes and leukaemia. Whereas the underlying cause is unknown, epigenetic change of …

Genetic risk factors for chronic kidney disease (CKD) are being identified through
international collaborations. By comparison, epigenetic risk factors for CKD have only …

Essential hypertension (EH) is a complex, polygenic condition with no single causative
agent. Despite advances in our understanding of the pathophysiology of EH, hypertension …