Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …
D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
Targeting innate immunity-driven inflammation in CKD and cardiovascular disease
T Speer, S Dimmeler, SJ Schunk, D Fliser… - Nature Reviews …, 2022 - nature.com
Mortality among patients with chronic kidney disease (CKD) is largely a consequence of
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …
Systemic immune-inflammation index is associated with increased urinary albumin excretion: a population-based study
Z Qin, H Li, L Wang, J Geng, Q Yang, B Su… - Frontiers in …, 2022 - frontiersin.org
Background Systemic immune-inflammation index (SII) is a novel inflammatory marker, and
inflammation has been reported to be related with renal damage. We aimed to investigate …
inflammation has been reported to be related with renal damage. We aimed to investigate …
The role of inflammation in CKD
SP Kadatane, M Satariano, M Massey, K Mongan… - Cells, 2023 - mdpi.com
Chronic kidney disease (CKD) affects many adults worldwide. Persistent low-grade
inflammation is a substantial factor in its development and progression and has correlated …
inflammation is a substantial factor in its development and progression and has correlated …
Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …
increased prevalence and incidence. In addition to its macrovascular damage, through its …
Klotho, oxidative stress, and mitochondrial damage in kidney disease
J Donate-Correa, B Martín-Carro, JB Cannata-Andía… - Antioxidants, 2023 - mdpi.com
Reducing oxidative stress stands at the center of a prevention and control strategy for
mitigating cellular senescence and aging. Kidney disease is characterized by a premature …
mitigating cellular senescence and aging. Kidney disease is characterized by a premature …
Short-chain fatty acids in chronic kidney disease: Focus on inflammation and oxidative stress regulation
G Magliocca, P Mone, BR Di Iorio, A Heidland… - International Journal of …, 2022 - mdpi.com
Chronic Kidney Disease (CKD) is a debilitating disease associated with several secondary
complications that increase comorbidity and mortality. In patients with CKD, there is a …
complications that increase comorbidity and mortality. In patients with CKD, there is a …
Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease
The glucagon receptor (GCGR) in the kidney is expressed in nephron tubules. In humans
and animal models with chronic kidney disease, renal GCGR expression is reduced …
and animal models with chronic kidney disease, renal GCGR expression is reduced …
Folic acid‐induced animal model of kidney disease
LJ Yan - Animal models and experimental medicine, 2021 - Wiley Online Library
The kidneys are a vital organ that is vulnerable to both acute kidney injury (AKI) and chronic
kidney disease (CKD) which can be caused by numerous risk factors such as ischemia …
kidney disease (CKD) which can be caused by numerous risk factors such as ischemia …
Recent advances in understanding Nrf2 agonism and its potential clinical application to metabolic and inflammatory diseases
Oxidative stress is a major component of cell damage and cell fat, and as such, it occupies a
central position in the pathogenesis of metabolic disease. Nuclear factor-erythroid-derived 2 …
central position in the pathogenesis of metabolic disease. Nuclear factor-erythroid-derived 2 …