Endometriosis: Etiology, pathobiology, and therapeutic prospects

PTK Saunders, AW Horne - Cell, 2021 - cell.com
Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

Endometrial function in women with polycystic ovary syndrome: a comprehensive review

S Palomba, TT Piltonen… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Uterine bleeding: how understanding endometrial physiology underpins menstrual health

V Jain, RR Chodankar, JA Maybin… - Nature reviews …, 2022 - nature.com
Menstruation is a physiological process that is typically uncomplicated. However, up to one
third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …

Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

L Garcia-Alonso, LF Handfield, K Roberts… - Nature …, 2021 - nature.com
The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout
the menstrual cycle in response to ovarian hormones. We have generated dense single-cell …

Evaluation of menstrual irregularities after COVID-19 vaccination: Results of the MECOVAC survey

AS Laganà, G Veronesi, F Ghezzi, MM Ferrario… - Open …, 2022 - degruyter.com
We investigated menstrual irregularities after the first and second doses of the COVID-19
vaccine. Women answered a customised online questionnaire (ClinicalTrial. gov ID …

Deciphering the endometrial niche of human thin endometrium at single-cell resolution

H Lv, G Zhao, P Jiang, H Wang… - Proceedings of the …, 2022 - National Acad Sciences
Thin endometrium has been widely recognized as a critical cause of infertility, recurrent
pregnancy loss, and placental abnormalities; however, access to effective treatment is a …

Endometrial receptivity in women of advanced age: an underrated factor in infertility

ADS Pathare, M Loid, M Saare, SB Gidlöf… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Modern lifestyle has led to an increase in the age at conception. Advanced
age is one of the critical risk factors for female-related infertility. It is well known that maternal …

Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion

J Ma, H Zhan, W Li, L Zhang, F Yun, R Wu, J Lin… - Biomaterials …, 2021 - Springer
Intrauterine adhesion (IUA) is a common gynaecological disease that develops from
infection or trauma. IUA disease may seriously affect the physical and mental health of …

Mechanisms of regeneration and fibrosis in the endometrium

CJ Ang, TD Skokan, KL McKinley - Annual review of cell and …, 2023 - annualreviews.org
The uterine lining (endometrium) regenerates repeatedly over the life span as part of its
normal physiology. Substantial portions of the endometrium are shed during childbirth …

Endometriosis: a disease with few direct treatment options

PRC França, ACP Lontra, PD Fernandes - Molecules, 2022 - mdpi.com
Endometriosis is a gynecological condition characterized by the growth of endometrium-like
tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility …