Noninvasive magnetic resonance imaging measures of glymphatic system activity
K Kamagata, Y Saito, C Andica… - Journal of Magnetic …, 2024 - Wiley Online Library
The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …
removal of interstitial solutes within the central nervous system (CNS), has witnessed …
Diffusion along perivascular spaces as marker for impairment of glymphatic system in Parkinson's disease
T Shen, Y Yue, F Ba, T He, X Tang, X Hu, J Pu… - npj Parkinson's …, 2022 - nature.com
The brain glymphatic system is involved in the clearance of misfolding α-synuclein, the
impaired glymphatic system may contribute to the progression of Parkinson's disease (PD) …
impaired glymphatic system may contribute to the progression of Parkinson's disease (PD) …
A critical guide to the automated quantification of perivascular spaces in magnetic resonance imaging
The glymphatic system is responsible for waste clearance in the brain. It is comprised of
perivascular spaces (PVS) that surround penetrating blood vessels. These spaces are filled …
perivascular spaces (PVS) that surround penetrating blood vessels. These spaces are filled …
Updates on brain regions and neuronal circuits of movement disorders in Parkinson's disease
J Wang, X Wang, H Li, L Shi, N Song, J Xie - Ageing Research Reviews, 2023 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disease with a global burden
that affects more often in the elderly. The basal ganglia (BG) is believed to account for …
that affects more often in the elderly. The basal ganglia (BG) is believed to account for …
Perivascular spaces mediate a relationship between diabetes and other cerebral small vessel disease markers in cerebrovascular and neurodegenerative diseases
J Zebarth, R Kamal, G Perlman, M Ouk… - Journal of Stroke and …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) and hypertension are risk factors for cerebral small vessel
disease (SVD); however, few studies have characterised their relationships with MRI-visible …
disease (SVD); however, few studies have characterised their relationships with MRI-visible …
Increased perivascular space volume in white matter and basal ganglia is associated with cognition in Parkinson's Disease
EK Donahue, RP Foreman, JJ Duran… - Brain Imaging and …, 2024 - Springer
Abstract Perivascular spaces (PVS), fluid-filled compartments surrounding brain vasculature,
are an essential component of the glymphatic system responsible for transport of waste and …
are an essential component of the glymphatic system responsible for transport of waste and …
Interplay between the glymphatic system and neurotoxic proteins in Parkinson's disease and related disorders: current knowledge and future directions
Y Yue, X Zhang, W Lv, HY Lai… - Neural Regeneration …, 2024 - journals.lww.com
Parkinson's disease is a common neurodegenerative disorder that is associated with
abnormal aggregation and accumulation of neurotoxic proteins, including α-synuclein …
abnormal aggregation and accumulation of neurotoxic proteins, including α-synuclein …
Experimental models to study immune dysfunction in the pathogenesis of Parkinson's disease
Parkinson's disease (PD) is a chronic, age-related, progressive multisystem disease
associated with neuroinflammation and immune dysfunction. This review discusses the …
associated with neuroinflammation and immune dysfunction. This review discusses the …
[HTML][HTML] The glymphatic system and multiple sclerosis: An evolving connection
A Alghanimy, LM Work, WM Holmes - Multiple Sclerosis and Related …, 2024 - Elsevier
Multiple sclerosis (MS) is a complex autoimmune disorder that affects the central nervous
system, resulting in demyelination and an array of neurological manifestations. Recently …
system, resulting in demyelination and an array of neurological manifestations. Recently …
Altered perivascular spaces in subcortical white matter in Parkinson's disease patients with levodopa-induced dyskinesia
X Cao, C Gan, H Zhang, Y Yuan, H Sun… - npj Parkinson's …, 2024 - nature.com
Dilated perivascular spaces (PVS) have emerged as a pathological hallmark in various
neurological conditions, including Parkinson's disease (PD). Levodopa-induced dyskinesia …
neurological conditions, including Parkinson's disease (PD). Levodopa-induced dyskinesia …